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Cooperativity and communication between the active sites of the dimeric SARS-CoV-2 main protease
Authors: Sarah N Zvornicanin, Ala M Shaqra, Julia Flynn, Lauren E Intravaia, Heidi Carias Martinez, Weiping Jia, Devendra Kumar Gupta, Stephanie Moquin, Dustin Dovala, Daniel N Bolon, Brian A Kelch, Celia A Schiffer, Nese Kurt Yilmaz
Journal: SCIENCE ADVANCES
PubMed ID: 41544157
Doi: 10.1126/sciadv.aeb0769
Products & Services: Molecular Biology Reagents   
FLIPs: Genetically encoded molecular biosensors for functional imaging of cell signaling by linear dichroism microscopy
Authors: Paul Miclea, Vendula Nagy-Marková, Robin Van den Eynde, Wim Vandenberg, Alina Sakhi, Alexey Bondar, Jitka Myšková, Peter Dedecker, Josef Lazar
Journal: SCIENCE ADVANCES
PubMed ID: 41544164
Doi: 10.1126/sciadv.adz5662
Products & Services: Gene Synthesis   
Optimally engineered HLA/peptide-specific CAR-T cells outperform TCR-T cells to eradicate solid tumors
Authors: Corinne E Decker, Jacqueline Idun, Katja Mohrs, Thomas Craig Meagher, Iryna Petriv, Jonathon Golas, Robert Salzler, Timothy Helms, Dharani Ajithdoss, Suhasini Avvaru, Jiaxi Wu, Tong Zhang, Eric Smith, Gavin Thurston, John C Lin, Jessica R Kirshner, David J DiLillo
Journal: SCIENCE ADVANCES
PubMed ID: 41564177
Doi: 10.1126/sciadv.adx9371
Products & Services: Gene Synthesis   
Dyslipidaemia-associated natural IgM improves oncolytic virus TILT-123 efficacy through antibody-dependent enhancement in solid tumours.
Authors: James Hugo Armstrong Clubb, Santeri Artturi Pakola, Sakari Joenväärä, Tatiana Viktorovna Kudling, Tiialotta Tohmola, Victor Arias, Elise Jirovec, Mirte van der Heijden, Dafne Carolina Alves Quixabeira, Annukka Pasanen, Lyna Haybout, Nea Ojala, Saru Basnet, Arianna Eleuteri, Julia Davila Ferrero, Stella Hirvenoja, Inge Marie Svane, Johanna Mäenpää, Katriina Jalkanen, Matthew Stephen Block, Tuomo Alanko, Tine Monberg, Sanae Zahraoui, Susanna Grönberg-Vähä-Koskela, Natasha Salmelin, Claudia Kistler, Riikka Havunen, Suvi Sorsa, João Manuel Dos Santos, Victor Cervera-Carrascon, Anna Kanerva, Otto Hemminki, Risto Renkonen, Akseli Hemminki
Journal: Molecular Therapy
PubMed ID: 41566775
Doi: 10.1016/j.ymthe.2026.01.019
Products & Services: Protein portfolio   
Human cytomegalovirus regulates host DNA repair machinery for viral genome integrity
Authors: Pierce Longmire, Sebastian Zeltzer, Kristen Zarrella, Olivia Daigle, Marek Svoboda, Justin M Reitsma, Scott S Terhune, Carly Bobak, Giovanni Bosco, Felicia Goodrum
Journal: Nucleic Acids Research
PubMed ID: 41533576
Doi: 10.1093/nar/gkaf1445
Products & Services: Protein Electrophoresis and Western   
Staufen dsRNA-binding domain as modules to design bifunctional antibodies for siRNA delivery
Authors: Yahui Liu, Yan Zheng, Ruolin Xu, Yanan Quan, Wanyi Tai
Journal: Nucleic Acids Research
PubMed ID: 41569158
Doi: 10.1093/nar/gkaf1539
Products & Services: Gene Synthesis   
Protection against lethal canine distemper virus infection by a dual epitope-targeting synthetic antibody
Authors: Melanie Scherer, Nadia Djabeur, Oliver Siering, Jean-Marc Jeckelmann, Marianne Wyss, Marina Cresci, Morgane Di Palma Subran, Rainer Riedl, Patrick Chames, Christian K Pfaller, Bevan Sawatsky, Dimitrios Fotiadis, Philippe Plattet
Journal: Nature Communications
PubMed ID: 41501035
Doi: 10.1038/s41467-025-67600-z
Products & Services: Monoclonal Antibody Services   
Mast cell-specific CysLT2 receptor signaling inhibits cysteinyl leukotriene-dependent mast cell activation and type 2 allergic lung inflammation
Authors: Jun Nagai, Madeline M Hastings, Airi Nishida, Sreyashi Majumdar, Kendall Zaleski, Sofia A Marshall, Junrui Lin, Mira A S Saliman, Yumi Tani, Yamato Murakami, Chunli Feng, Alexander Perniss, Caitlin Wong, Lora G Bankova, Asuka Inoue, Nora A Barrett, Joshua A Boyce
Journal: Cell Reports
PubMed ID: 41422505
Doi: 10.1016/j.celrep.2025.116758
Products & Services: Custom Vector Construction   
Cooked meat-derived extracellular vesicles ssc-miR-1 induces metabolic disorders in the mice liver via PI3k/AKT pathway
Authors: Linyuan Shen, Jianfeng Ma, Shuang Liang, Yiting Yang, Tianci Liao, Yuhang Lei, Lei Chen, Yan Wang, Ye Zhao, Lili Niu, Mailin Gan, Li Zhu
Journal: NPJ science of food
PubMed ID: 41577711
Doi: 10.1038/s41538-026-00709-7
Products & Services: Protein Electrophoresis and Western   
Targeting WTAP/ROR1/WNT5A-Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy
Authors: Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai
Journal: Advanced Science
PubMed ID: 41562250
Doi: 10.1002/advs.202520661
Products & Services: Protein Electrophoresis and Western