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CD3ɛ Nanobody-Engineered Extracellular Vesicles Driving In Vivo Generation of BiTE-Secreting CAR-Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity
Authors: Shi-Wei Huang, Yu-Chuan Lin, Chih-Ming Pan, Yeh Chen, Ming-You Shie, Cheng-Yu Chen, Kai-Wen Kan, Yi-Wen Chen, Ming-Chao Liu, Chung-Chun Wu, Yu-Ting Chiang, Huai-Ping Ho, Chen-Yu Lin, Pei-Ying Lin, Yu-Han Huang, Steffany Rusli, Wan-Yu Mao, Pei-Wen Huang, Sin-Ting Wang, Wan-Chen Tsai, Ya-Hsu Chiu, Ting-Hsun Lin, Wan-Ling Chiang, Che-Kai Chang, Zi-Lun Lai, Mei-Chih Chen, Shao-Chih Chiu, Der-Yang Cho
Journal: Advanced Science
PubMed ID: 41632088
Doi: 10.1002/advs.202519440
Safe and Highly Efficient Lipid-Pro-Dexamethasone Nanoparticles for mRNA Delivery and Base Editing
Authors: Yan Zong, Haiping Zhong, Yuqing Wang, Yi Lin, Linxi Zhao, Xiaoyu Wang, Jianan Cai, Haoyang Lin, Yixi Xiao, Tuo Wei, Shutao Guo, Qiang Cheng
Journal: Journal of the American Chemical Society
PubMed ID: 41733506
Doi: 10.1021/jacs.6c01708
Products & Services: Synthetic Guide RNA   
Identifying microbial protease allergens through protein language model-guided homology
Authors: Kumar Thurimella, Elena Wu, Chenhao Li, Daniel B Graham, Róisín M Owens, Damian R Plichta, Caroline L Sokol, Ramnik J Xavier, Sergio Bacallado
Journal: Molecular Therapy
PubMed ID: 41722567
Doi: 10.1016/j.cels.2025.101510
Messenger RNA delivery to islet β cells using conjugated lipid nanoparticles
Authors: Jacob R Enriquez, Zhengjie Zhou, Jennifer B Nelson, Fei Huang, Kayla T Figatner, Advaita Chakraborty, Sarida Pratuangtham, Brian Xi, Sarah C May, Matthew V Tirrell, Sarah A Tersey, Yun Fang, Raghavendra G Mirmira
Journal: Molecular Therapy
PubMed ID: 41722565
Doi: 10.1016/j.xcrm.2026.102634
Products & Services: Recombinant Proteins   
Functional characterization of secreted Schistosoma mansoni serpin SmSPI reveals Factor XIIa inhibition as evidenced by biochemical, and human plasma assays and supported by AI-assisted structural modelling
Authors: Lukáš Konečný, Kristýna Peterková, Ingrid Hrachovinová, Alex Loukas, Tomáš Macháček, Jan Dvořák, Lucie Jedličková
Journal: Molecular Therapy
PubMed ID: 41724421
Doi: 10.1016/j.ijpara.2026.104808
NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2
Authors: Luzheng Zhang, Yu Zhang, Dezhong Wen, Suxiang Guo, Xiaohui Qi, Heng Wang, Yujin Sun, Guangdong Yang, Yuehong Wang, Song Xue
Journal: Advanced Science
PubMed ID: 41637534
Doi: 10.1002/advs.202505240
Products & Services: Protein Electrophoresis and Western   
Characterization of gRNA-dependent and gRNA-independent off-target binding sites of PspCas13b and RfxCas13d in mammalian cells
Authors: Huanhuan Feng, Zhixue Li, Hongdao Zhang, Yuli Zheng, Beiying Xu, Yao Zhang, Lin Zou, Ligang Wu
Journal: Nucleic Acids Research
PubMed ID: 41728952
Doi: 10.1093/nar/gkag112
Human DNA polymerase η is regulated by mutually exclusive mono-ubiquitination and mono-NEDDylation
Authors: Natália C Moreno, Emilie J Korchak, Marcela T Latancia, Dana A D'Orlando, Temidayo Adegbenro, Ryan P Barnes, Irina Bezsonova, Roger Woodgate, Nicholas W Ashton
Journal: Nucleic Acids Research
PubMed ID: 41693564
Doi: 10.1093/nar/gkag098
PolyP inhibits CobB deacetylase triggering a regulatory coupling to prevent DNA replication initiation
Authors: Ewelina Boguszewska, Zuzanna Hirsz, Magdalena Sroka, Katarzyna Bury, Weronika Chmura, Agnieszka Strzałka, Marta Kołodziej, Jolanta Zakrzewska-Czerwińska, Igor Konieczny
Journal: Nucleic Acids Research
PubMed ID: 41728951
Doi: 10.1093/nar/gkag144
GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton
Authors: Guilin Wang, Qingxin Si, Zhiguo Chen, Zhe Yu, Zhan Guo, Lu Wang, Weixi Li, Wangzhen Guo
Journal: Advanced Science
PubMed ID: 41521460
Doi: 10.1002/advs.202515724
Products & Services: Catalog Antibodies