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De novo design of protein condensation inhibitors by targeting an allosteric site of cGAS

Authors: Wenfeng Zhao, Guofeng Chen, Jian He, Xiaofang Shen, Muya Xiong, Liwei Xiong, Zhihao Qi, Hang Xie, Wanchen Li, Jiameng Li, Huixia Dou, Hangchen Hu, Haixia Su, Qiang Shao, Minjun Li, Hongbin Sun, Yechun Xu

Journal: Nature Communications

PubMed ID: 40461475

Doi: 10.1038/s41467-025-60297-0

Products & Services: Gene Synthesis

Functional relocation of the maize chloroplast atpB gene to the nucleus restores photosynthetic competence to a gene-edited non-photosynthetic mutant

Authors: Venkata RamanaRao Mangu, Kelsey Jenkins, Anna Pratt, Kara A Boltz, Leila Pazouki, Alice Y Hui, Muruganantham Mookkan, Jeffrey M Staub

Journal: Plant Biotechnology Journal.

PubMed ID: 40467523

Doi: 10.1111/pbi.70175

Products & Services: Catalog Antibodies

Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap-DNAs and Alleviating Pulmonary Fibrosis

Authors: Yibo Du, Chenxu Zhu, Ruifeng Wang, Shi Chen, Chuang Li, Defang OuYang, Lixin Liu, Yongming Chen

Journal: Advanced Science

PubMed ID: 40539399

Doi: 10.1002/advs.202505357

Topoisomerase I Inhibition in ETV4-overexpressed Non-Small Cell Lung Cancer Promotes Replication and Transcription Mediated R-Loop Accumulation and DNA Damage

Authors: Jiaxi Zhang, Yan Wang, Shanhu Cao, Shelly M Xie, Bei Liu, Yimeng Li, Yuqi Hou, Xue Meng, Mingzhu Ruan, Di Bu, Jia Kang, Ruxin Li, Lei Lou, Juan Wang, Lingxiao Xing

Journal: Advanced Science

PubMed ID: 40548893

Doi: 10.1002/advs.202409307

Products & Services: PCR Cloning and Subcloning

ATP13A1 engages SEC61 to facilitate substrate-specific translocation

Authors: Xiaoyan Yang, Yi Li, Chengxi Yang, Tingting Li, Zhiyu Fang, Zhigang Feng, Jun Liao, Yan Zou

Journal: SCIENCE ADVANCES

PubMed ID: 40498833

Doi: 10.1126/sciadv.adt1346

Products & Services: Protein and Antibody Isolation

LPS-enriched interaction drives spectrum conversion in antimicrobial peptides: Design and optimization of AA16 derivatives for targeting gram-negative bacteria

Authors: Wanyang Xiao, Ruize Sun, Jietao Lou, Yanyan Xu, Xiaokun Li, Kaiyun Xin, Weijie Lu, Chenhui Sun, Tianbao Chen, Yitian Gao, Di Wu

Journal: Eur J Med Chem

PubMed ID: 40048797

Doi: 10.1016/j.ejmech.2025.117462

Products & Services: Peptide Synthesis

Chondrocyte fatty acid oxidation drives osteoarthritis via SOX9 degradation and epigenetic regulation

Authors: Zixuan Mei, Kamuran Yilamu, Weiyu Ni, Panyang Shen, Nan Pan, Huasen Chen, Yingfeng Su, Lei Guo, Qunan Sun, Zhaomei Li, Dongdong Huang, Xiangqian Fang, Shunwu Fan, Haitao Zhang, Shuying Shen

Journal: nature COMMUNICATION

PubMed ID: 40425566

Doi: 10.1038/s41467-025-60037-4

Products & Services: Catalog Antibodies Protein and Antibody Isolation

MechanismsofaureobasidinA inhibition and drug resistance in a fungal IPC synthase complex

Authors: Xinyue Wu , Xin Gong , Tian Xie

Journal: nature COMMUNICATION

PubMed ID: 40442105

Doi: doi.org/10.1038/s41467-025-60423-y

Products & Services: Protein and Antibody Isolation

DNA-Engineered Modular Nanovaccines Featuring Precise Topology for Enhanced Immunogenicity

Authors: Yanfei Qu, Dawei Wang, Yunlong Zhang, Fengyun Shen, Binghui Xia, Qin Xu, Qisheng Wang, Huating Kong, Ying Zhu, Lihua Wang, Itamar Willner, Xiurong Yang, Chunhai Fan, Lele Sun

Journal: ADVANCED MATERIALS

PubMed ID: 40371439

Doi: 10.1002/adma.202500577

Products & Services: Protein and Antibody Reagents

Deep Proteomic Profiling of the Intra-Golgi Trafficking Intermediates

Authors: Farhana Taher Sumya , Walter S Aragon-Ramirez , Vladimir V Lupashin

Journal: Molecular biology of the cell

PubMed ID: 40397568

Doi: 10.1091/mbc.E24-12-0556

Products & Services: Gene Synthesis

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