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Discovery and identification of a novel small molecule BCL-2 inhibitor that binds to the BH4 domain

Authors: Jing-Yi Zhou, Rui-Rui Yang, Jie Chang, Jia Song, Zi-Sheng Fan, Ying-Hui Zhang, Cheng-Hao Lu, Hua-Liang Jiang, Ming-Yue Zheng, Su-Lin Zhang

Journal: Acta Pharmacol Sin

PubMed ID: 35918411

Doi: 10.1038/s41401-022-00936-0

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A Localized Materials-Based Strategy to Non-Virally Deliver Chondroitinase ABC mRNA Improves Hindlimb Function in a Rat Spinal Cord Injury Model

Authors: Andrew S Khalil, Daniel Hellenbrand, Kaitlyn Reichl, Jennifer Umhoefer, Mallory Filipp, Joshua Choe, Amgad Hanna, William L Murphy

Journal: Adv Healthc Mater

PubMed ID: 35882512

Doi: 10.1002/adhm.202200206

Products & Services: Plasmid DNA Preparation

The NCF1 variant pR90H aggravates autoimmunity by facilitating the activation of plasmacytoid dendritic cells

Authors: Yao Meng, Jianyang Ma, Chao Yao, Zhizhong Ye, Huihua Ding, Can Liu, Jun Li, Guanhua Li, Yuke He, Jia Li, Zhihua Yin, Li Wu, Haibo Zhou, Nan Shen

Journal: J Clin Invest

PubMed ID: 35788118

Doi: 10.1172/JCI153619

Products & Services: Protein and Antibody Isolation

Novel prime-boost immune-based therapy inhibiting both hepatitis B and D virus infections

Authors: Rani Burm, Panagiota Maravelia, Gustaf Ahlen, Sandra Ciesek, Noelia Caro Perez, Anna Pasetto, Stephan Urban, Freya Van Houtte, Lieven Verhoye, Heiner Wedemeyer, Magnus Johansson, Lars Frelin, Matti Sällberg, Philip Meuleman

Journal: Gut

PubMed ID: 35977815

Doi: 10.1136/gutjnl-2022-327216

Products & Services: Protein and Antibody Isolation

PpZAT10 negatively regulates peach cold resistance predominantly mediated by inhibiting VIN activity

Authors: YiChen ,JiachangSun ,YingyingWei ,KefengCao ,ShuJiang ,XingfengShao

Journal: Postharvest Biology and Technology

Doi: 10.1016/j.postharvbio.2022.111952

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A novel ZsGreen knock-in melanoma cell line reveals the function of CD11b in tumor phagocytosis

Authors: Lichen Zhang, Xinyu Feng, Yingzhuo Shen, Yingbin Wang, Zhuangzhuang Liu, Yuang Ma, Yanrong Gu, Guo Guo, Liangwei Duan, Liaoxun Lu, Yinming Liang, Toby Lawrence, Rong Huang

Journal: Immunol Cell Biol

PubMed ID: 35849045

Doi: 10.1111/imcb.12575

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Antibody affinity and cross-variant neutralization of SARS-CoV-2 Omicron BA1, BA2 and BA3 following third mRNA vaccination

Authors: Lorenza Bellusci, Gabrielle Grubbs, Fatema Tuz Zahra, David Forgacs, Hana Golding, Ted M Ross, Surender Khurana

Journal: Nat Commun

PubMed ID: 35941152

Doi: 10.1038/s41467-022-32298-w

Products & Services: PCR Cloning and Subcloning

Third Early "Booster" Dose Strategy in France of bnt162b2 SARS-CoV-2 Vaccine in Allogeneic Hematopoietic Stem Cell Transplant Recipients Enhances Neutralizing Antibody Responses

Authors: Abdelhakim Ahmed-Belkacem, Rabah Redjoul, Rozenn Brillet, Nazim Ahnou, Mathieu Leclerc, Dennis Salomón López-Molina, Alexandre Soulier, Aurélie Gourgeon, Christophe Rodriguez, Sébastien Maury, Jean-Michel Pawlotsky, Slim Fourati

Journal: Viruses

PubMed ID: 36146735

Doi: 10.3390/v14091928

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The effect of substance P and its common in vivo-formed metabolites on MRGPRX2 and human mast cell activation

Authors: Lin Hsin, Nithya A Fernandopulle, Jie Ding, Chris Lumb, Nicholas Veldhuis, John A Karas, Susan E Northfield, Graham A Mackay

Journal: Pharmacol Res Perspect

PubMed ID: 35904495

Doi: 10.1002/prp2.990

Products & Services: Mammalian Expression

Expanding the antiviral potential of the mosquito lipid-transfer protein AEG12 against SARS-CoV-2 using hydrophobic antiviral ligands

Authors: Alexander C Y Foo, Bernard A P Lafont, Geoffrey A Mueller

Journal: FEBS Lett

PubMed ID: 35891619

Doi: 10.1002/1873-3468.14456

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