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Stimulator of interferon genes (STING) provides insect antiviral immunity by promoting Dredd caspase-mediated NF-κB activation.

Authors: HuaXiaoting，LiBinbin，SongLiang，HuCuimei，LiXianyang，WangDandan，XiongYing，ZhaoPing，HeHuawei，XiaQingyou，Wan

Journal: J. Biol. Chem.

PubMed ID: 29875158

Doi: 10.1074/jbc.RA117.000194

Products & Services: Recombinant Proteins

Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer.

Authors: XiangQiuping，WangChao，ZhangYan，XueXiaoqian，SongMing，ZhangCheng，LiChenchang，WuChun，LiKuai，HuiXiaoyan，ZhouYulai，SmaillJeff B，PattersonAdam V，WuDonghai，DingKe，Xu

Journal: Eur J Med Chem

PubMed ID: 29448139

Doi: 10.1016/j.ejmech.2018.01.087

Products & Services: Peptide Synthesis

A structurally dynamic N-terminal region drives function of the staphylococcal peroxidase inhibitor (SPIN).

Authors: de JongNienke W M，PloscariuNicoleta T，RamyarKasra X，GarciaBrandon L，HerreraAlvaro I，PrakashOm，KatzBenjamin B，LeidalKevin G，NauseefWilliam M，van KesselKok P M，van StrijpJos A G，GeisbrechtBri

Journal: J. Biol. Chem.

PubMed ID: 29306874

Doi: 10.1074/jbc.RA117.000134

Products & Services: Peptide Synthesis

Decoding the Divergent Subcellular Location of Two Highly Similar Paralogous LEA Proteins.

Authors: Avelange-MacherelMarie-Hélène，CandatAdrien，NeveuMartine，TolleterDimitri，MacherelD

Journal: Int J Mol Sci

PubMed ID: 29857468

Doi: 10.3390/ijms19061620

Products & Services: Peptide Synthesis

Dietary Total Prenylflavonoids from the Fruits of Psoralea corylifolia L. Prevents Age-Related Cognitive Deficits and Down-Regulates Alzheimer's Markers in SAMP8 Mice.

Authors: Zhi-Jing Chen, Yan-Fang Yang, Ying-Tao Zhang and Dong-Hui Yang