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Prokaryotic Gabija complex senses and executes nucleotide depletion and DNA cleavage for antiviral defense
Authors: Rui Cheng , Fengtao Huang , Xueling Lu , Yan Yan , Bingbing Yu , Xionglue Wang , Bin Zhu
Journal: Cell Host Microbe .
PubMed ID: 37480847
Doi: 10.1016/j.chom.2023.06.014
Products & Services: Custom DNA/RNA Oligos   
Perdeuterated GbpA Enables Neutron Scattering Experiments of a Lytic Polysaccharide Monooxygenase
Authors: H V Sørensen, Mateu Montserrat-Canals, Jennifer S M Loose, S Zoë Fisher, Martine Moulin, Matthew P Blakeley, Gabriele Cordara, Kaare Bjerregaard-Andersen, Ute Krengel
Journal: ACS Omega
PubMed ID: 37599915
Doi: 10.1021/acsomega.3c02168
Products & Services: Proteins, Expression, Isolation and Analysis   
Viral manipulation of cell polarity signalling
Authors: Airah Javorsky, Patrick O Humbert, Marc Kvansakul
Journal: Biochim Biophys Acta Mol Cell Res
PubMed ID: 37437846
Doi: 10.1016/j.bbamcr.2023.119536
Products & Services: Molecular Biology Reagents   
Mesothelin-targeting T cell receptor fusion construct cell therapy in refractory solid tumors: phase 1/2 trial interim results
Authors: Raffit Hassan, Marcus Butler, Roisin E O'Cearbhaill, David Y Oh, Melissa Johnson, Kevin Zikaras, Munisha Smalley, Michael Ross, Janos L Tanyi, Azam Ghafoor, Nirali N Shah, Babak Saboury, Liang Cao, Alfonso Quintás-Cardama, David Hong
Journal: Nat Med
PubMed ID: 37501016
Doi: 10.1038/s41591-023-02452-y
Products & Services: Proteins, Expression, Isolation and Analysis   
Macrophage infectivity potentiator protein, a peptidyl prolyl cis-trans isomerase, essential for Coxiella burnetii growth and pathogenesis
Authors: Aleksandra W Debowski, Nicole M Bzdyl, David R Thomas, Nichollas E Scott, Christopher H Jenkins, Jua Iwasaki, Emily A Kibble, Chen Ai Khoo, Nicolas J Scheuplein, Pamela M Seibel, Theresa Lohr, Georgie Metters, Charles S Bond, Isobel H Norville, Keith A Stubbs, Nicholas J Harmer, Ulrike Holzgrabe, Hayley J Newton, Mitali Sarkar-Tyson
Journal: PLoS Pathog
PubMed ID: 37399210
Doi: 10.1371/journal.ppat.1011491
Products & Services: Proteins, Expression, Isolation and Analysis   
Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins
Authors: Ashley P Viera Ortiz, Gregory Cajka, Olamide A Olatunji, Bailey Mikytuck, Ophir Shalem, Edward B Lee
Journal: Brain
PubMed ID: 36516294
Doi: 10.1093/brain/awac479
Products & Services: DNA Sequencing   
Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1
Authors: Eva-Maria Thüring, Christian Hartmann, Janesha C Maddumage, Airah Javorsky, Birgitta E Michels, Volker Gerke, Lawrence Banks, Patrick O Humbert, Marc Kvansakul, Klaus Ebnet
Journal: Commun Biol
PubMed ID: 37430142
Doi: 10.1038/s42003-023-05088-3
Products & Services: Peptide Synthesis   Click Peptide Services   
Enhancement of the viability of T cells electroporated with DNA via osmotic dampening of the DNA-sensing cGAS–STING pathway
Authors: Jing An , Chuan-Ping Zhang , Hou-Yuan Qiu , Hong-Xia Zhang , Qiu-Bing Chen , Yu-Ming Zhang , Xin-Lin Lei , Cai-Xiang Zhang , Hao Yin , Ying Zhang
Journal: Nat Biomed Eng .
PubMed ID: 37500747
Doi: 10.1038/s41551-023-01073-7
Products & Services: CRISPR Plasmids   
The combination of osimertinib with Raf inhibitor overcomes osimertinib resistance induced by KRAS amplification in EGFR-mutated lung cancer cells
Authors: Tae-Gul Lee, Hye-Min Kang, Seo Yun Kim, Hye-Ryoun Kim, Cheol Hyeon Kim
Journal: Exp Cell Res
PubMed ID: 37442265
Doi: 10.1016/j.yexcr.2023.113722
Products & Services: Proteins, Expression, Isolation and Analysis   
Combined Inhibition of the TGF-β1/Smad Pathway by and to Reduce Inflammation and Fibrosis in Primary Sclerosing Cholangitis
Authors: Yu Shen, Baorong Jiang, Chenchen Zhang, Qian Wu, Lei Li, Ping Jiang
Journal: Int J Mol Sci
PubMed ID: 37446187
Doi: 10.3390/ijms241311010
Products & Services: Proteins, Expression, Isolation and Analysis