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Regulatory oversight of cell therapy in China: Government's efforts in patient access and therapeutic innovation

Authors: Weijia Wu, Yuanyuan Wang, Zhijia Tang, Yuan Gao, Yan Huo

Journal: Pharmacol Res

PubMed ID: 32428666

Doi: 10.1016/j.phrs.2020.104889

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Retargeting CD19 CAR T cells via engineered CD19-fusion proteins

Authors: Klesmith JR, Su L, Wu L, Schrack IA, Dufort FJ, Birt A, Ambrose C, Hackel BJ, Lobb RR, Rennert PD.

Journal: Mol Pharm

PubMed ID: 31242389

Doi: 10.1021/acs.molpharmaceut.9b00418

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B cell maturation antigen (BCMA)-based immunotherapy for multiple myeloma.

Authors: Tai YT, Anderson KC.

Journal: Expert Opin Biol Ther

PubMed ID: 31277554

Doi: 10.1080/14712598.2019.1641196

Products & Services: Recombinant Proteins

Chimeric antigen receptor (CAR) T therapies for the treatment of hematologic malignancies: clinical perspective and significance.

Authors: Boyiadzis Michael M，Dhodapkar Madhav V，Brentjens Renier J，Kochenderfer James N，Neelapu Sattva S，Maus Marcela V，Porter David L，Maloney David G，Grupp Stephan A，Mackall Crystal L，June Carl H，Bishop Micha

Journal: J Immunother Cancer

PubMed ID: 30514386

Doi: 10.1186/s40425-018-0460-5

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The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity.

Authors: HelsenChristopher W，HammillJoanne A，LauVivian W C，MwawasiKenneth A，AfsahiArya，BezverbnayaKsenia，NewhookLisa，HayesDanielle L，AartsCraig，BojovicBojana，DenisovaGalina F，KwiecienJacek M，BrainIan，DerocherHeather，MilneKaty，NelsonBrad H，BramsonJonath

Journal: Nat Commun

PubMed ID: 30076299

Doi: 10.1038/s41467-018-05395-y

Products & Services: Gene Synthesis

A phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or refractory multiple myeloma.

Authors: Zhao WH, Liu J, Wang BY, Chen YX, Cao XM, Yang Y, Zhang YL, Wang FX, Zhang PY, Lei B, Gu LF, Wang JL, Yang N, Zhang R, Zhang H, Shen Y, Bai J, Xu Y, Wang XG, Zhang RL, Wei LL, Li ZF, Li ZZ, Geng Y, He Q, Zhuang QC, Fan XH, He AL,, Zhang WG.

Journal: J Hematol Oncol

PubMed ID: 30572922

Doi: 10.1186/s13045-018-0681-6

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Public biotech in 2017-the numbers.

Authors: MorrisonChris，Lähteenmäki

Journal: Nat. Biotechnol.

PubMed ID: 29979653

Doi: 10.1038/nbt.4175

Products & Services: CRISPR Cell Line Engineering

Generation and characterization of human B lymphocyte stimulator blocking monoclonal antibody.

Authors: Zhuang W, Zhang J, Pei L, Fang S, Liu H, Wang R, Su Y.

Journal: Mol Immunol.

PubMed ID: 27505709

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Molecular Characterization of Equine APRIL and its Expression Analysis During the Adipogenic Differentiation of Equine Adipose-Derived Stem Cell In Vitro.

Authors: WuHaitao，BiXiaolin，CaoFang，ZhuCuicui，LiuHongzhen，SongJinyun，MaLei，MaLi，ZhangYi，ZhaoDongwei，LiuHongyan，XuXinzhou，ZhangShuang

Journal: Anim. Biotechnol.

PubMed ID: 27565870

Doi: 10.1080/10495398.2016.1182540

Products & Services: Gene Synthesis

Enhanced Immunogenicity of HIV-1 Envelope gp140 Proteins Fused to APRIL.

Authors: G Isik, K Sliepen, T van Montfort, RW Sanders.

Journal: PLoS One. 9(9):e107683

PubMed ID: 25247707

Products & Services: Gene Synthesis

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