GenScript - Make Research Easy - The leader in molecular cloning and gene synthesis, peptide synthesis,protein and antibody engineering.

CD22 TCR-engineered T cells exert antileukemia cytotoxicity without causing inflammatory responses

Authors: Kilyna A Nguyen, Zhihui Liu, John S Davies, Crystal P McIntosh, Lindsey M Draper, Scott M Norberg, Zachary Rae, Sooraj R Achar, Gregoire Altan-Bonnet, Ling Zhang, Xiaolin Wu, Thomas J Meyer, Michael C Kelly, Naomi Taylor, Christian S Hinrichs, Kazusa Ishii

Journal: SCIENCE ADVANCES

PubMed ID: 40203088

Doi: 10.1126/sciadv.adq4297

Products & Services: Gene Synthesis

The CD8α hinge is intrinsically disordered with a dynamic exchange that includes proline cis-trans isomerization

Authors: Xiang Chen, Justin M Mirazee, Katarzyna A Skorupka, Hiroshi Matsuo, Philippe Youkharibache, Naomi Taylor, Kylie J Walters

Journal: J Magn Reson

PubMed ID: 35617919

Doi: 10.1016/j.jmr.2022.107234

Products & Services: Custom Vector Construction

Construction of a Large Size Human Immunoglobulin Heavy Chain Variable (VH) Domain Library, Isolation and Characterization of Novel Human Antibody VH Domains Targeting PD-L1 and CD22

Authors: Zehua Sun, Wei Li, John W Mellors, Rimas Orentas, Dimiter S Dimitrov

Journal: Front Immunol

PubMed ID: 35464476

Doi: 10.3389/fimmu.2022.869825

Products & Services: Protein and Antibody Isolation

Nanobody-based anti-CD22-chimeric antigen receptor T cell immunotherapy exhibits improved remission against B-cell acute lymphoblastic leukemia

Authors: Tingting Zhang, Tian Wang, Fengtao You, Zixuan Li, Dan Chen, Kailu Zhang, Shuaiyu Tian, Binjie Sheng, Hai Wu, Licui Jiang, Renyuxue Ma, Gangli An, Huimin Meng, Lin Yang

Journal: Transpl Immunol

PubMed ID: 35051588

Doi: 10.1016/j.trim.2022.101538

Products & Services: Catalog Antibodies

Immunoglobulin a suppresses B cell receptor-mediated activation of mouse B cells with differential inhibition of signaling molecules

Authors: Kouya Yamaki, Masato Terashi, Saori Yamamoto, Rei Fujiwara, Jun-Ichi Inoue, Kishi Shimizu, Sakura Yanagita, Yuma Doi, Kei-Ichiro Kimura, Kayo Kotani, Mai Sugihara, Yutaka Koyama

Journal: Immunopharmacol Immunotoxicol

PubMed ID: 34844505

Doi: 10.1080/08923973.2021.2006216

Products & Services: Endotoxin Detection & Removal System

Adjuvant ruxolitinib therapy relieves steroid-refractory cytokine-release syndrome without impairing chimeric antigen receptor-modified T-cell function

Authors: Shuning Wei, Runxia Gu, Yingxi Xu, Xiaoyu Liu, Yanyan Xing, Xiaoyuan Gong, Chunlin Zhou, Bingcheng Liu, Guangji Zhang, Kaiqi Liu, Hui Wei, Yingchang Mi, Min Wang, Ying Wang, Jianxiang Wang

Journal: Immunotherapy

PubMed ID: 32777959

Doi: 10.2217/imt-2020-0116

Products & Services: Gene Fragments

Bacterial expression and characterization of an anti-CD22 single-chain antibody fragment

Authors: Mikiewicz D, Łukasiewicz N, Zieliński M, Cecuda-Adamczewska V, Bierczyńska-Krzysik A, Romanik-Chruścielewska A, Kęsik-Brodacka M.

Journal: Protein Expr Purif

PubMed ID: 32032771

Products & Services: Custom Vector Construction

A tandem CD19/CD20 CAR lentiviral vector drives on-target and off-target antigen modulation in leukemia cell lines.

Authors: Schneider D,Xiong Y,Wu D,Nӧlle V,Schmitz S,Haso W,Kaiser A,Dropulic B,Orentas RJ.

Journal: J Immunother Cancer.

PubMed ID: 28515942

Products & Services: Protein and Antibody Isolation

A novel siglec (CgSiglec-1) from the Pacific oyster (Crassostrea gigas) with broad recognition spectrum and inhibitory activity to apoptosis, phagocytosis and cytokine.

Authors: Liu C, Jiang S, Wang M, Wang L, Chen H, Xu J, Lv Z, Song L.

Journal: Dev Comp Immunol.

PubMed ID: 27032602

Products & Services: Catalog Antibodies

A CD22-reactive TCR from the T-cell allorepertoire for the treatment of acute lymphoblastic leukemia by TCR gene transfer.

Authors: JahnLorenz，HagedoornRenate S，van der SteenDirk M，HombrinkPleun，KesterMichel G D，SchoonakkerMarjolein P，de RidderDaniëlle，van VeelenPeter A，FalkenburgJ H Frederik，HeemskerkMirjam

Journal: Oncotarget

PubMed ID: 27689397

Doi: 10.18632/oncotarget.12247

Products & Services: DNA Sequencing

全部