A GM-CSF-neuroantigen tolerogenic vaccine elicits inefficient antigen recognition events below the CD40L triggering threshold to expand CD4+ CD25+ FOXP3+ Tregs that inhibit experimental autoimmune encephalomyelitis (EAE)
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(MEVGWYRSPFSRVVH- LYRNGK) and NFM13–37 (RRVTETRSSFSRVSGSPSSGF RSQS) were obtained from Genscript (Piscataway |
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