| Products/Services Used | Details | Operation |
|---|---|---|
| Gene Synthesis | … had N-terminal leader sequences (SEQ ID No: 5). Design of the Expression Plasmids. Genes encoding for a truncated OmpA with the SpyTag sequence appended to the either the N-terminus, C-terminus, or an internal loop were synthesized by GenScript (Piscataway, NJ) in a … | Get A Quote |
Nanoparticle-based therapeutics are poised to play a critical role in treating disease. These complex multifunctional drug delivery vehicles provide for the passive and active targeted delivery of numerous small molecule, peptide and protein-derived pharmaceuticals. This article will first discuss some of the current state of the art nanoparticle classes (dendrimers, lipid-based, polymeric and inorganic), highlighting benefits/drawbacks associated with their implementation. We will then discuss an emerging class of nanoparticle therapeutics, bacterial outer membrane vesicles, that can provide many of the nanoparticle benefits while simplifying assembly. Through molecular biology techniques; outer membrane vesic... More
