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Effects of RHAMM/HMMR-Selective Peptides on Survival of Breast Cancer Cells.

Bull. Exp. Biol. Med.. 2015;

Akent'eva N P，Shushanov S S，Kotel'nikov

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摘要

RHAMM-selective peptides in a concentration of 10 μg/ml (2×10(-7) M) inhibited the growth of MDA-MB-231 breast cancer cells over 48 h. Treatment of cancer cells with RHAMM-selective peptides induced apoptosis and necrosis and increased caspase-3 activity (by 30%).