Products/Services Used | Details | Operation |
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DNA Sequencing> | were extracted for preliminary identification by enzyme digestion and sequencing (Nanjing GenScript | Get A Quote |
We aimed to explore the relationship between miR-126 and glioma. miR-126 was highly expressed in low-grade clinical glioma tissue samples but lowly expressed in high-grade ones (P?.01). A human endogenous miR-126 expression vector was constructed. The migration capacity of cells transfected with the vector significantly decreased (P?.05). Up-regulation of miR-126 suppressed GATA4 protein expression. After transfection, they slightly contracted and became ovally or spherically shaped. F-actin significantly reduced, and microfilaments shortened or disappeared. The number of membrane-penetrating cells significantly decreased (P?.01). miR-126 inhibits the migration and invasion of glioma cells, which ma... More