资源 » 参考数据库 » 客户发表文献

至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

ACPAs promote IL-1β production in rheumatoid arthritis by activating the NLRP3 inflammasome.

Cell. Mol. Immunol.. 2019-03;

DongXiwen，ZhengZhaohui，LinPeng，FuXianghui，LiFanni，JiangJianli，Zhu

Products/Services Used	Details	Operation
Molecular Biology Reagents	The content of ACPA IgG was verified by SPR. The control IgG was pooled from healthy individuals’ serum using similar methods. Endotoxin was removed with a Toxin EraserTM endotoxin removal kit (GenScript, NJ, USA)	Get A Quote

摘要

Anti-citrullinated protein antibodies (ACPAs) are a group of autoantibodies targeted against citrullinated proteins/peptides and are informative rheumatoid arthritis (RA) biomarkers. ACPAs also play a crucial role in RA pathogenesis， and their underlying mechanism merits investigation.