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Expression of Nodal on Bronchial Epithelial Cells Influenced by Lung Microbes Through DNA Methylation Modulates the Differentiation of T-Helper Cells.

Cell. Physiol. Biochem.. 2015; 
WangLili,WuGuojun,QinXiaoqun,MaQiongshan,ZhouYigang,LiuShuiping,TanYu
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Custom Vector Construction To generate the siRNA expression construct of Nodal, three siRNA sequences (GenScript, China) were cloned into the pGCU6/Neo/RFP vector respectively. Get A Quote

摘要

The previous study in our lab showed that Nodal molecule on bronchial epithelial cells (BECs) was modulated by all kinds of lung microbes. The present study was designed to determine the effects of Nodal on proliferation of BECs and BECs-induced differentiation of T-helper (Th) cells. The epigenetic mechanisms of Nodal expression following treatments of different lung microbes were also identified.

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