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Asprosin improves the survival of mesenchymal stromal cells in myocardial infarction by inhibiting apoptosis via the activated ERK1/2-SOD2 pathway.

Life Sci.. 2019;

ZhangZhengbin，TanYanzhen，ZhuLiwen，ZhangBing，FengPan，GaoErhe，XuChennian，WangXiaoming，YiWei，Sun

Products/Services Used	Details	Operation
Gene Synthesis	… cat. no. RR820A; Takara); GAPDH served as the qPCR amplification endogenous control. PCR primers were purchased from GenScript Biotech Corp. (Nanjing, China); the primer sequences are listed in Table S1. Heml Heatmap …	Get A Quote

摘要

Several adipokines have been proven to improve the therapeutic efficacy of mesenchymal stromal cells (MSCs) when used to treat ischemic heart disease. Asprosin (ASP) is a newly-discovered adipokine. ASP might also predict the severity of coronary pathology. We investigated the role of ASP on MSCs and the effects of ASP-pretreated MSCs on myocardial infarction (MI).