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Rational design of hypoallergens applied to the major cat allergen Fel d 1.

Clin. Exp. Allergy. 2016-04;

SaarneT，KaiserL，GrönlundH，RasoolO，GafvelinG，van Hage-Hams

Products/Services Used	Details	Operation
Peptide Synthesis	… Ara h 1 peptides (Mimotopes, Victoria, Australia and GenScript USA Inc, New Jersey, USA; Table S3) were reconstituted at 2 mg/mL in 10% dimethyl sulfoxide/PBS (20-mers and truncated peptide sets) or PBS alone (custom-synthesized core epitope peptides) …	Get A Quote

摘要

Allergen-specific immunotherapy is the only treatment for allergic disease providing long-lasting symptom relief. Currently， it is mainly based on the use of crude allergen extracts. The treatment may be improved by the use of genetically engineered allergens， hypoallergens， aiming at a more effective and safer therapy.