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An antihypertensive lactoferrin hydrolysate inhibits angiotensin I-converting enzyme, modifies expression of hypertension-related genes and enhances nitric oxide

Journal of functional foods 2015. 2015;

García-Tejedor, Aurora, Gimeno-Alcañíz, José V., Tavárez, Sandra, Alonso, Eulalia, Salom, Juan B., Manzanares, Paloma

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Peptide Synthesis	… Peptides of sequences LIWKL and RPYL were purchased at >95% purity from GenScript Corporation (Piscataway, NJ, USA), wherein they were synthesized by solid phase methods using N-(9-fluorenyl) methoxycarbonyl (Fmoc) chemistry …	Get A Quote

摘要

This study was aimed to explore whether an antihypertensive lactoferrin hydrolysate (LFH) can inhibit angiotensin I-converting enzyme (ACE) activity and modify the expression of genes related to hypertension in human umbilical vein endothelial cells (HUVEC).