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Degradation of the benzoxazolinone class of phytoalexins is important for virulence of Fusarium pseudograminearum towards wheat.

Mol. Plant Pathol.. 2015; 
KettleAndrew J,BatleyJacqueline,BenfieldAurelie H,MannersJohn M,KazanKemal,GardinerDona
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Gene Synthesis To delete FDB2 from F. graminearum, a construct was synthesized by GenScript (Piscataway, NJ, USA) Get A Quote

摘要

Wheat, maize, rye and certain other agriculturally important species in the Poaceae family produce the benzoxazolinone class of phytoalexins on pest and pathogen attack. Benzoxazolinones can inhibit the growth of pathogens. However, certain fungi can actively detoxify these compounds. Despite this, a clear link between the ability to detoxify benzoxazolinones and pathogen virulence has not been shown. Here, through comparative genome analysis of several Fusarium species, we have identified a conserved genomic region around the FDB2 gene encoding an N-malonyltransferase enzyme known to be involved in benzoxazolinone degradation in the maize pathogen Fusarium verticillioides. Expression analyses demon... More

关键词

Fusarium graminearum,Fusarium pseudograminearum,benzoxazolinone,crown rot,head blight,phenoxazinone,phytoal