| Products/Services Used | Details | Operation |
|---|---|---|
| Peptide Synthesis | … 21 Synthetic bovine BCM peptides The synthetic bovine β–CN–derived peptides YPF (f60–62, BCM3), YPFP (f60–63, BCM4), YPFPG (f60–64, BCM5), YPFPGP (f60–65, BCM6) and YPFPGPI (f60–66, BCM7) were purchased from GenScript (Piscataway, NJ, USA) 22 … | Get A Quote |
The current live vaccinia virus vaccine used in the prevention of smallpox is contraindicated for millions of immune-compromised individuals. Although vaccination with the current smallpox vaccine produces protective immunity， it might result in mild to serious health complications for some vaccinees. Thus， there is a critical need for the production of a safe virus-free vaccine against smallpox that is available to everyone. For that reason， we investigated the impact of imiquimod and resiquimod (Toll-like receptors agonists)， and the codon-usage optimization of the vaccinia virus A27L gene in the enhancement of the immune response， with intent of producing a safe， virus-free DNA vaccine coding for... More
