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Loganin attenuates diabetic nephropathy in C57BL/6J mice with diabetes induced by streptozotocin and fed with diets containing high level of advanced glycation end products.

Life Sci.. 2015-02; 
LiuKai,XuHuiqin,LvGaohong,LiuBin,LeeMaxwell Kim Kit,LuChunhong,LvXing,WuYu
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Gene Synthesis … All primers were obtained from GenScript (Piscataway, NJ, USA), and are listed as follows: α-SMA: (forward) 5′-CTGAGACGGGACTCTTTACACTGC-3′, (reverse) 5′- TATTCCACCTTCAGGCTCAACCA-3′; β-actin: (forward) 5′-AGGGAAATCGTGCGTGACTTCA … Get A Quote

摘要

Diabetic nephropathy is the most common cause of end-stage renal disease in patients with diabetes. Advanced glycation end-products (AGEs) play a prominent role in the development of diabetic nephropathy. We herein evaluated the effects of loganin on diabetic nephropathy in vivo.

关键词

Advanced glycation end-products,Diabetes mellitus,Diabetic nephropathy,Kidney,Log