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Induction of squamous cell carcinoma after MAP3K8 overexpression in murine salivry gland epithelial cells.

Head Neck. 2019; 
LeeJun-Han,JeongJoseph H,KimTae-Hwan,KimSo-Yeon,KimKyung-Eun,SeongJe Kyung,LeeSang
Products/Services Used Details Operation
Gene Synthesis … To confirm tumorigenesis of salivary gland, the following antibodies were used for detection: MAP3K8 Cen. (1:250, generated using the GenScript)6; Ki‐67 (1:500, Cat. #15580, Abcam); cytokeratin‐5 (1:200, cat. # PRB‐160P, COVANCE); and cytokeratin‐8 (1:200, cat … Get A Quote

摘要

Salivary gland neoplasms are relatively rare and comprise only 1%-4% of all human neoplasms. Salivary gland neoplasms also show an extremely wide range of morphological diversity. Currently, the genetic alterations and corresponding molecular mechanisms underlying salivary gland neoplasms development remain largely unknown.

关键词

MAP3K8,salivary gland,squamous cell carcinoma,transgenic mouse,tumorigen