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MOV10 binding circ-DICER1 regulates the angiogenesis of glioma via miR-103a-3p/miR-382-5p mediated ZIC4 expression change.

J. Exp. Clin. Cancer Res.. 2019-01; 
HeQianru, ZhaoLini, LiuXiaobai, ZhengJian, LiuYunhui, LiuLibo, MaJun, CaiHeng, LiZhen, XueY
Products/Services Used Details Operation
Gene Synthesis … ZIC4 (NM_001168378.1) full length (with 3′-UTR) plasmid, ZIC4 (without 3′-UTR) plasmid (GenScript, Piscataway, NJ, USA), short-hairpin ZIC4 plasmid (GenePharma, Shanghai, China) and their respective non-targeting sequence (negative control, NC) were constructed … Get A Quote

摘要

RNA binding proteins (RBPs) have been reported to interact with RNAs to regulate gene expression. Circular RNAs (circRNAs) are a type of endogenous non-coding RNAs, which involved in the angiogenesis of tumor. The purpose of this study is to elucidate the potential roles and molecular mechanisms of MOV10 and circ-DICER1 in regulating the angiogenesis of glioma-exposed endothelial cells (GECs).

关键词

Angiogenesis,Circ-DICER1,Gliomas,MOV10,miR-103a-3p,miR-38