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microRNA-690 regulates induced pluripotent stem cells (iPSCs) differentiation into insulin-producing cells by targeting Sox9.

Stem Cell Res Ther. 2019-03;

XuYang, HuangYan, GuoYibing, XiongYicheng, ZhuShajun, XuLiancheng, LuJingjing, LiXiaohong, WanJian, LuYuhua, WangZh

Products/Services Used	Details	Operation
Gene Synthesis	… Each experiment was performed independently and repeated three times. The qRT-PCR primer sequences were designed and synthesized by GenScript Biotech Corp. (Nanjing, China). miRNA microarray assay and bioinformatic analysis of target genes …	Get A Quote

摘要

The regulatory mechanism of insulin-producing cells (IPCs) differentiation from induced pluripotent stem cells (iPSCs) in vitro is very important in the phylogenetics of pancreatic islets， the molecular pathogenesis of diabetes， and the acquisition of high-quality pancreatic β-cells derived from stem cells for cell therapy.