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The pro-inflammatory effects of particulate matter on epithelial cells are associated with elemental composition.

Chemosphere. 2018-07;

ShaoJingyi，WheelerAmanda J，ChenLing，StrandbergBo，HinwoodAndrea，JohnstonFay H，ZoskyGrae

Products/Services Used	Details	Operation
Proteins, Expression, Isolation and Analysis	… Endotoxin levels in 57 μg/mL PM suspension were assessed once for each sample prior to exposing the cells using a chromogenic limulus amebocyte lysate (LAL) assay kit (GenScript, Piscataway, NJ) according to the manufacturer's instructions …	Get A Quote

摘要

Adverse health effects of particulate matter (PM) vary with chemical composition; however， evidence regarding which elements are the most detrimental is limited. The roof space area provides an open and stable environment for outdoor PM to settle and deposit. Therefore， this study used roof space PM samples as a proxy of residential cumulative exposure to outdoor air pollution to investigate their pro-inflammatory effects on human lung cells and the contribution of the endotoxin and chemical content.