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Fiprole insecticide resistance of Laodelphax striatellus: electrophysiological and molecular docking characterization of A2'N RDL GABA receptors.

Pest Manag. Sci.. 2018-11;

ShengCheng-Wang，CasidaJohn E，DurkinKathleen A，ChenFeng，HanZhao-Jun，ZhaoChun-

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Recombinant Proteins	… VIS spectrophotometer (Thermo Fisher Scientific, Inc.), diluted to 543 ng μL-1 and stored at -80 oC until use. The recombinant expression plasmids for LsRDL protein were confirmed by sequencing in GenScript. Xenopus laevis was anesthetized by immersion in ice for 30 min …	Get A Quote

摘要

Phenylpyrazole (fiprole) insecticides， including ethiprole， fipronil and flufiprole with excellent activity on rice planthoppers， are very important in Asia but resistance has developed after decades of use. The molecular mechanism of fipronil- but not ethiprole-resistance has been previously studied in rice planthoppers. In our laboratory， a small brown planthopper Laodelphax striatellus strain with ethiprole-resistance was cultured and the molecular mechanisms of ethiprole resistance and of cross-resistance among fiprole insecticides were investigated.