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A uniquely efficacious type of CFTR corrector with complementary mode of action

Authors: Valentina Marchesin, Lucile Monnier, Peter Blattmann, Florent Chevillard, Christine Kuntz, Camille Forny, Judith Kamper, Rolf Studer, Alexandre Bossu, Eric A Ertel, Oliver Nayler, Christine Brotschi, Jodi T Williams, John Gatfield

Journal: SCIENCE ADVANCES

PubMed ID: 38427726

Doi: 10.1126/sciadv.adk1814

Products & Services: PCR Cloning and Subcloning

FUS reads histone H3K36me3 to regulate alternative polyadenylation

Authors: Junqi Jia, Haonan Fan, Xinyi Wan, Yuan Fang, Zhuoning Li, Yin Tang, Yanjun Zhang, Jun Huang, Dong Fang

Journal: Nucleic Acids Research

PubMed ID: 38499486

Doi: 10.1093/nar/gkae184

Products & Services: Protein and Antibody Isolation

Phage-displayed synthetic library and screening platform for nanobody discovery

Authors: Baolong Xia; Ah-Ram Kim; Feimei Liu; Myeonghoon Han; Emily Stoneburner; Stephanie Makdissi; Francesca Di Cara; Stephanie E Mohr; Aaron Ring; Norbert Perrimon; Ahmad S Khalil; Baolong Xia; Ah-Ram Kim; Feimei Liu; Myeonghoon Han; Emily Stoneburner; Stephanie Makdissi; Francesca Di Cara; Stephanie E Mohr; Aaron Ring; Norbert Perrimon

Journal: Elife

PubMed ID: 40748049

Doi: 10.7554/eLife.105887

Products & Services: Protein and Antibody Isolation

Phage-displayed synthetic library and screening platform for nanobody discovery

Journal: Elife

PubMed ID: 40748049

Doi: 10.7554/eLife.105887

Products & Services: Protein and Antibody Isolation

Inhibition of a conserved bacterial dual-specificity phosphatase confers plant tolerance to Candidatus Liberibacter spp

Authors: Haoqi Wang; Sonia Irigoyen; Jiaxing Liu; Manikandan Ramasamy; Carmen Padilla; Renesh Bedre; Chuanyu Yang; Shree P. Thapa; Nirmitee Mulgaonkar; Veronica Ancona; Ping He; Gitta Coaker; Sandun Fernando; Kranthi K. Mandadi

Journal: iScience

PubMed ID: 38425843

Doi: 10.1016/j.isci.2024.109232

Products & Services: Monoclonal Antibody Services

G-quadruplexes control hepatitis B virus replication by promoting cccDNA transcription and phase separation in hepatocytes

Authors: Guillaume Giraud, Mélanie Rodà, Pélagie Huchon, Maud Michelet, Sarah Maadadi, Daniel Jutzi, Roland Montserret, Marc-David Ruepp, Romain Parent, Christophe Combet, Fabien Zoulim, Barbara Testoni

Journal: Nucleic Acids Res

PubMed ID: 38113270

Doi: 10.1093/nar/gkad1200

Products & Services: Mutagenesis Services

Interferon-γ in the tumor microenvironment promotes the expression of B7H4 in colorectal cancer cells, thereby inhibiting cytotoxic T cells

Authors: Zhi-Liang Jing, Guang-Long Liu, Na Zhou, Dong-Yan Xu, Na Feng, Yan Lei, Li-Li Ma, Min-Shan Tang, Gui-Hui Tong, Na Tang, Yong-Jian Deng

Journal: Nature

PubMed ID: 38480774

Doi: 10.1038/s41598-024-56681-3

Products & Services: Polyclonal Antibody Services

Molecular basis for substrate transport of Mycobacterium tuberculosis ABC importer DppABCD

Authors: Tianyu Hu, Xiaolin Yang, Yuanchen Zhu, Fengjiang Liu, Xiuna Yang, Zhiqi Xiong, Jingxi Liang, Zhenli Lin, Yuting Ran, Luke W Guddat, Zihe Rao, Bing Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 38507491

Doi: 10.1126/sciadv.adk8521

Products & Services: Protein and Antibody Isolation

MIWI N-terminal arginines orchestrate generation of functional pachytene piRNAs and spermiogenesis

Authors: Nicholas Vrettos, Jan Oppelt, Ansgar Zoch, Paraskevi Sgourdou, Haruka Yoshida, Brian Song, Ryan Fink, Dónal O'Carroll, Zissimos Mourelatos 1

Journal: Nucleic Acids Research

PubMed ID: 38520410

Doi: 10.1093/nar/gkae193

Products & Services: Peptide Synthesis

An intein-based biosensor to measure protein stability in vivo

Authors: Ahyun Son, John S Smetana, Scott Horowitz , Christopher W Lennon

Journal: Protein Sci

PubMed ID: 38380775

Doi: 10.1002/pro.4925

Products & Services: Gene Synthesis