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Co-delivery of Cas9 mRNA and guide RNAs for editing of LGMN gene represses breast cancer cell metastasis

Authors: Yue Wang, Yatu Peng, Guanghui Zi, Jin Chen, Baowei Peng

Journal: Sci Rep

PubMed ID: 38582932

Doi: 10.1038/s41598-024-58765-6

Products & Services: Protein and Antibody Isolation

CoCas9 is a compact nuclease from the human microbiome for efficient and precise genome editing

Authors: Eleonora Pedrazzoli, Michele Demozzi, Elisabetta Visentin, Matteo Ciciani, Ilaria Bonuzzi, Laura Pezzè, Lorenzo Lucchetta, Giulia Maule, Simone Amistadi, Federica Esposito, Mariangela Lupo, Annarita Miccio, Alberto Auricchio, Antonio Casini, Nicola Segata, Anna Cereseto

Journal: Nat Commun

PubMed ID: 38658578

Doi: 10.1038/s41467-024-47800-9

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy

Authors: Madison A Ward, Janakiram R Vangala, Hatem Elif Kamber Kaya, Holly A Byers, Nayyerehalsadat Hosseini, Antonio Diaz, Ana Maria Cuervo, Susmita Kaushik, Senthil K Radhakrishnan

Journal: J Cell Biol

PubMed ID: 38656405

Doi: 10.1083/jcb.202306150

Products & Services: Molecular Biology Reagents

Doxorubicin induces phosphorylation of lamin A/C and loss of nuclear membrane integrity: A novel mechanism of cardiotoxicity

Authors: Vikas Tiwari, Paras Gupta, Navya Malladi, Sanjay Salgar, Sanjay K Banerjee

Journal: Free Radic Biol Med

PubMed ID: 38582228

Doi: 10.1016/j.freeradbiomed.2024.04.212

Products & Services: ORF cDNA Clones/MolecularCloud

Icariin attenuates vascular endothelial dysfunction by inhibiting inflammation through GPER/Sirt1/HMGB1 signaling pathway in type 1 diabetic rats

Authors: Wenhui Yao, Rongpin Tao, Kai Wang, Xuansheng Ding

Journal: Chin J Nat Med

PubMed ID: 38658093

Doi: 10.1016/S1875-5364(24)60618-7

Products & Services: Molecular Biology Reagents

Correction: Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtained from systemic sclerosis patients affected by interstitial lung disease

Authors: Stefano Soldano, Vanessa Smith, Paola Montagna, Emanuele Gotelli, Rosanna Campitiello, Carmen Pizzorni, Sabrina Paolino, Alberto Sulli, Andrea Cere, Maurizio Cutolo

Journal: Arthritis Res Ther

PubMed ID: 38600545

Doi: 10.1186/s13075-024-03319-4

Products & Services: Protein and Antibody Isolation

Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial

Authors: Mark Yarchoan, Edward J Gane, Thomas U Marron, Renzo Perales-Linares, Jian Yan, Neil Cooch, Daniel H Shu, Elana J Fertig, Luciane T Kagohara, Gabor Bartha, Josette Northcott, John Lyle, Sarah Rochestie, Joann Peters, Jason T Connor, Elizabeth M Jaffee, Ildiko Csiki, David B Weiner, Alfredo Perales-Puchalt, Niranjan Y Sardesai

Journal: Nat Med

PubMed ID: 38584166

Doi: 10.1038/s41591-024-02894-y

Products & Services: Molecular Biology Reagents

Chimeric Porcine Parvovirus VP2 Virus-like Particles with Epitopes of South African Serotype 2 Foot-and-Mouth Disease Virus Elicits Specific Humoral and Cellular Responses in Mice

Authors: Qian Li, Xusheng Ma, Yaner Shen, Junfei Dai, Xiaofeng Nian, Xiaofen Shang, Jiao Chen, Ashenafi Kiros Wubshet, Jie Zhang, Haixue Zheng

Journal: Viruses

PubMed ID: 38675963

Doi: 10.3390/v16040621

Products & Services: Gene Synthesis

The Hsa_circ_0105558/miR-182-5p/ATF6 Cascade Affects HO-Triggered Oxidative Damage and Apoptosis of Human Lens Epithelial Cells

Authors: Wei Mao, Zhe Zhang

Journal: Biochem Genet

PubMed ID: 38530576

Doi: 10.1007/s10528-024-10753-1

Products & Services: Molecular Biology Reagents

Diagnosis of fasciolosis antibodies in Brazilian cattle through ELISA employing both native and recombinant antigens

Authors: Guilherme Drescher, Hellen Geremias Dos Santos, Mariane Marques da Guarda Pinto, Luis Gustavo Morello, Fabiano Borges Figueiredo

Journal: Microbiol Spectr

PubMed ID: 38534120

Doi: 10.1128/spectrum.00095-24

Products & Services: Molecular Biology Reagents