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页码: 16/5356 每页显示数量

Systematic analysis of functional genetic and epigenetic variants in colorectal cancer

Authors: Erfei Chen, Qiqi Yang, Haoyang Dai, Yixin Chen, Yihui Zhang, Qianglong Wang, Rongrong Hou, Ming Chen, Jie Wang, Qianwen Xie, Wenju Sun, Yong-Qiang Ning, Ligang Fan, Jian Yan

Journal: SCIENCE ADVANCES

PubMed ID: 41719390

Doi: https://doi.org/10.1126/sciadv.aeb2473

Products & Services: NGS Oligos

Abstract Supplement Abstracts from AIDS 2022 the 24th International AIDS Conference, 29 July 2 August 2022, Montr al, Canada & Virtual

Authors:

Journal: Journal of the International AIDS Society

PubMed ID: 35916394

Doi: 10.1002/jia2.25935

Computational engineering of the polyester hydrolase PHL7 for efficient poly(ethylene terephthalate) degradation in biocatalytic recycling processes

Authors: Paula Bl zquez-S nchez; Jonas Gunkel; Abibe Useini; Alexander Zlobin; Jonathan D. Zakary; Andrea Sch ler; Norbert Graefe; Felipe Engelberger; Filipa Cantanhede; Ronny Frank; Ziyue Zhao; Afsaneh Zarei; Erik Butensch n; J rg Matysik; Wolfgang Zimmermann; Norbert Str ter; Christian Sonnendecker; Georg K nze

Journal: Nature Communications

PubMed ID: 42140896

Doi: 10.1038/s41467-026-70868-4

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Personalized structural biology reveals the molecular mechanisms underlying heterogeneous epileptic phenotypes caused by de novo KCNC2 variants

Authors: Souhrid Mukherjee; Thomas A. Cassini; Ningning Hu; Tao Yang; Bian Li; Wangzhen Shen; Christopher W. Moth; David C. Rinker; Jonathan H. Sheehan; Joy D. Cogan; John H. Newman; Rizwan Hamid; Robert L. Macdonald; Dan M. Roden; Jens Meiler; Georg Kuenze; John A. Phillips; John A. Capra

Journal: Human Genetics and Genomics Advances

PubMed ID: 36035247

Doi: 10.1016/j.xhgg.2022.100131

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In-silico and in-vitro study of novel antimicrobial peptide AM1 from Aegle marmelos against drug-resistant Staphylococcus aureus

Authors: Rudra Awdhesh Kumar Mishra; Gothandam Kodiveri Muthukaliannan

Journal: Scientific REPORTS

PubMed ID: 39468175

Doi: 10.1038/s41598-024-76553-0

Products & Services: Peptide Synthesis

Rapid discovery of repurposed drugs targeting SARS-CoV-2 spike HR1 by DNA-encoded library screening

Authors: Qingao Xue, Ze Liang, Yi Zhang, Fei Wang, Fulian Wang, Lili Liu, Guang Yang, Lei Yan

Journal: Bioorganic Chemistry

PubMed ID: 41691755

Doi: 10.1016/j.bioorg.2026.109627

Products & Services: Peptide Synthesis

PD-L1-Binding Antigen Presenters: Redirecting Vaccine-Induced Antibodies for Cancer Immunotherapy

Authors: Huixin Gao, Lijuan Lu, Xiaoxiao Xiong, Yi Li, Donghui Hu, Duo Zhang, Zhiwei Feng, Cong Liu, Nannan Liu, Xiaoli Li, Jizhou Tan, Ting Liu, Ling Peng, Lu Lu, Huiyi Feng, Yan Zhong, Guisen Tan, Zhicheng Zhang, Liqin Huang, Chao Su, Ying Xue, Shuo Song, Wenxia Fan, Wei Wang, Fan Zou

Journal: Advanced Science

PubMed ID: 41668552

Doi: 10.1002/advs.202519574

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cPLA2α targeting to exosomes connects nuclear deformation to LTB4-signaling during neutrophil chemotaxis

Authors: Subhash B Arya, Fatima Jordan-Javed, Kristen Loesel, Yehyun Choi, Samuel P Collie, Lauren E Hein, Brendon M Baker, Euisik Yoon, Carole A Parent

Journal: SCIENCE ADVANCES

PubMed ID: 41719396

Doi: 10.1126/sciadv.aea2784

Trypanosome histone variants H3.V and H4.V promote nucleosome plasticity in repressed chromatin

Authors: Gauri Deák, Hayden Burdett, James A Watson, Marcus D Wilson

Journal: Molecular Therapy

PubMed ID: 41709455

Doi: 10.1016/j.str.2026.01.008

Products & Services: Codon Optimization

Syndecan-1-targeted therapeutic antibody impairs macropinocytosis and elicits antitumor immunity in pancreatic cancer

Authors: Zecheng Yang, Madelaine S Theardy, Shuaitong Chen, Yongkun Wei, Mitsunobu Takeda, Yue Zeng, Xiaofei Wang, Jun Yao, Jennifer Li, Prapassorn Thirasastr, Jangho Park, Yangxi Zheng, Long T Vien, Khalida M Wani, Huamin Wang, Sisi Gao, Tim Heffernan, Lawrence Kwong, Ignacio I Wistuba, Laura Bover, Giulio F Draetta, Haoqiang Ying, Wantong Yao

Journal: Molecular Therapy

PubMed ID: 41707651

Doi: 10.1016/j.xcrm.2026.102613