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Engineering precision zebrafish alleles of human disease

Authors: Holly R. Thomas; Bradley K. Yoder; Matthew S. Alexander; John M. Parant

Journal: biorxiv

PubMed ID: 40475461

Doi: 10.1101/2025.05.18.654701

Products & Services: Molecular Biology Reagents

The herpes simplex origin-binding protein: mechanisms for sequence-specific DNA binding and dimerization revealed by Cryo-EM

Authors: Emil Gustavsson; Kay Gr newald; Per Elias; B Martin H llberg

Journal: Nucleic Acids Research

PubMed ID: 41125242

Doi: 10.1093/nar/gkaf1029

Evaluation of AlphaFold modeling for elucidation of nanobody–peptide epitope interactions

Authors: Shivani Sachdev, Swarnali Roy, Shubhra J Saha, Gengxiang Zhao, Rashmi Kumariya, Brendan A Creemer, Rui Yin, Brian G Pierce, Carole A Bewley, Ross W Cheloha

Journal: The Journal of Biological Chemistry

PubMed ID: 40409557

Doi: 10.1016/j.jbc.2025.110268

Products & Services: Codon Optimization

Systemic administration of an RNA binding and cell- penetrating antibody targets therapeutic RNA to multiple mouse models of cancer

Authors: Elias Quijano, Diana Martinez-Saucedo, Zaira Ianniello, Natasha Pinto-Medici, Madison Rackear, Haoting Chen, Luiz Lola-Pereira, Yanfeng Liu, Denise Hegan, Xinning Shan, Robert Tseng, Deanne Yugawa, Sumedha Chowdhury, Minsoo Khang, Jay P Singh, Rashed Abdullah, Perisa Azhir, Soki Kashima, Wendy S Woods, Nicholas Gosstola, Bruce C Turner, Stephen Squinto, Dale L Ludwig, Ranjit S Bindra, Marie E Robert, David A Braun, Pablo Perez Pinera, W Mark Saltzman, Luisa F Escobar-Hoyos, Peter M Glazer

Journal: Science Translation Medicine

PubMed ID: 40668891

Doi: 10.1126/scitranslmed.adk1868

Products & Services: Recombinant Antibody Expression Stable Cell Lines

CONSTANT PH MOLECULAR DYNAMICS OF PORCINE CIRCOVIRUS 2 CAPSID PROTEIN REVEALS A MECHANISM FOR CAPSID ASSEMBLY

Authors: Elvira Tarasova; Noriaki Okimoto; Shanshan Feng; Dmitry Nerukh; Reza Khayat; Makoto Taiji

Journal: Physical chemistry chemical physics : PCCP

PubMed ID: 34726674

Doi: 10.1039/d1cp02874j

Products & Services: Plasmid DNA Preparation

Synergistic chemo-immunotherapy for osteosarcoma via a pH-responsive multi-component nanoparticle system

Authors: Dapeng Li; Yuanfan Li; Jie Cang; Xianwen Yan; Feipeng Wu; Xuan Sun; Wenchao Zhang

Journal: Frontiers in pharmacology

PubMed ID: 40264674

Doi: 10.3389/fphar.2025.1584245

Products & Services: Peptide Synthesis

Resistance to oxyimino-cephalosporins conferred by an alternative mechanism of hydrolysis by the Acinetobacter -derived cephalosporinase-33 (ADC-33), a class C -lactamase present in carbapenem-resistant Acinetobacter baumannii (CR Ab )

Authors: Rachel A. Powers; Bradley J. Wallar; Hannah R. Jarvis; Zoe X. Ziegler; Cynthia M. June; Christopher R. Bethel; Andrea M. Hujer; Magdalena A. Taracila; Susan D. Rudin; Kristine M. Hujer; Fabio Prati; Emilia Caselli; Robert A. Bonomo

Journal: MBio

PubMed ID: 40377322

Doi: 10.1128/mbio.00287-25

Deep Receptor Scanning Reveals General Sequence Constraints on GPCR Biosynthesis

Authors: Austin Tedman; Muskan Goel; Sohan Shah; Mathew K. Howard; Laura M. Chamness; Antonio Bonifasi; Ismalia Adams; Jacklyn M. Gallagher; Wesley D. Penn; Katarina Nemec; Eli F. McDonald; Brianna N. Corman; J. Paul Robinson; Carol Beth Post; Patricia L. Clark; M. Madan Babu; Aashish Manglik; Charles P. Kuntz; Willow Coyote-Maestas; Jonathan P. Schlebach

Journal: biorxiv

PubMed ID: 41000614

Doi: 10.1101/2025.09.19.677468

Visualization of a multi-turnover Cas9 after product release

Authors: Kaitlyn A. Kiernan & David W. Taylor

Journal: Nature Communications

PubMed ID: 40593576

Doi: 10.1038/s41467-025-60668-7

Products & Services: Synthetic Guide RNA

Molecular architecture and catalytic mechanism of human glycogen debranching enzyme

Authors: Huiyi Guan, Huan Chen, He Geng, Ruifang Ma, Zhongmin Liu, Yong Wang, Yifang Chen, Kaige Yan

Journal: Nature Communications

PubMed ID: 40593796

Doi: 10.1038/s41467-025-61077-6

Products & Services: Protein and Antibody Isolation