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A human-specific regulatory mechanism revealed in a pre-implantation model

Authors: Raquel Fueyo, Sicong Wang, Olivia J. Crocker, Tomek Swigut, Hiromitsu Nakauchi & Joanna Wysocka

Journal: Nature

PubMed ID: 41034587

Doi: 10.1038/s41586-025-09571-1

DLFea4AMPGen de novo design of antimicrobial peptides by integrating features learned from deep learning models

Authors: Han Gao, Feifei Guan, Boyu Luo, Dongdong Zhang, Wei Liu, Yuying Shen, Lingxi Fan, Guoshun Xu, Yuan Wang, Tao Tu, Ningfeng Wu, Bin Yao, Huiying Luo, Yue Teng, Jian Tian, Huoqing Huang

Journal: Nature Communications

PubMed ID: 41093853

Doi: 10.1038/s41467-025-64378-y

Virus-inspired lipopeptide-derived nucleic acid delivery to cartilage for osteoarthritis therapy

Authors: Yu Fu, Yulan Huang, Yunjiao Wang, Zhenlan Fu, Wenyun Cai, Lu Wang, Yuchun Wu, Xing Zhou, Zhongyi Ma, Zhigang Xu, Yaqin Tang, Jing Xie, Jiayun Jiang, Robert J. Lee & Chong Li

Journal: Nature Communications

PubMed ID: 41102140

Doi: 10.1038/s41467-025-64212-5

DNA StairLoop: enabling high-fidelity data recovery and robust error correction in DNA-based data storage

Authors: Zihui Yan, Guanjin Qu, Xin Chen, Gang Zheng & Huaming Wu

Journal: Nature Communications

PubMed ID: 41102205

Doi: 10.1038/s41467-025-64230-3

The nuclear import receptor importin-7 targets HPV from the Golgi to the nucleus to promote infection

Authors: Tai-Ting Woo, Yuka Takeo, Mara C Harwood, Ethan T Houck, Daniel DiMaio, Billy Tsai

Journal: SCIENCE ADVANCES

PubMed ID: 41124246

Doi: 10.1126/sciadv.adz6792

Mechanism-based peroxiredoxin 3 inhibitors exploit a covalent warhead for cancer therapy

Authors: Kimberly J Nelson, Terrence L Smalley Jr, Terri Messier, Rajesh Gumpena, Uma Gandhi, Stephanie Milczarek, Aida Habibovic, Hattie Hoffman, Victoria Gibson, Robert J Hondal, W Todd Lowther, Brian Cunniff

Journal: SCIENCE ADVANCES

PubMed ID: 41171914

Doi: 41171914

Baculovirus-Mediated Gene Therapy: Targeting BIRC6 for Lung and Breast Cancer

Authors: Abril Marchesini, Santiago M Gómez Bergna, Leslie C Amorós Morales, María Florencia López, Larisa Vásquez, Silvana E Tongiani, Florencia González Morán, Víctor Romanowski, María Florencia Gottardo, Matias L Pidre

Journal: Viruses

PubMed ID: 41305480

Doi: 10.3390/v17111458

Products & Services: PCR Cloning and Subcloning Plasmid DNA Preparation

Rabies virus-vectored Lyme disease vaccine provides long-term protection against tick-transmitted Borrelia burgdorferi

Authors: Shantel Rios; Bibek Bhattachan; Christoph Wirblich; Anisha Chandwani; Kruthi Vavilikolanu; Jacob F. Myers; Chrysoula Kitsou; Utpal Pal; Matthias J. Schnell

Journal: npj Vaccines

PubMed ID: 41233361

Doi: 10.1038/s41541-025-01294-8

Rabies virus-vectored Lyme disease vaccine provides long-term protection against tick-transmitted Borrelia burgdorferi

Authors: Shantel Rios; Bibek Bhattachan; Christoph Wirblich; Anisha Chandwani; Kruthi Vavilikolanu; Jacob F. Myers; Chrysoula Kitsou; Utpal Pal; Matthias J. Schnell

Journal: npj Vaccines

PubMed ID: 41233361

Doi: 10.1038/s41541-025-01294-8

Protocol for production and characterization of SARS-CoV-2 PL pro in Escherichia coli

Authors: Anna De Falco; Rebecca Greene-Cramer; Ben A. Shurina; Suren Zakian; Thomas B. Acton; Theresa A. Ramelot; Gaetano T. Montelione

Journal: STAR Protocols

PubMed ID: 40682779

Doi: 10.1016/j.xpro.2025.103952