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Targeting Protein Protein Interactions (PPIs) to Drive Functional Annotation: An Integrative Methodology to Study Senescence-Associated PPIs Using TMPRSS11a as Model Interactor

Authors: Roberto Rosales-Rojas; Christian Fern ndez; Mariela Gonz lez-Avenda o; Ariela Vergara-Jaque; M nica C ceres

Journal: Biomolecules

PubMed ID: 42194062

Doi: 10.3390/biom16050714

Structural insights into kainate receptor desensitization

Authors: Changping Zhou, Guadalupe Segura-Covarrubias, Nami Tajima

Journal: Nature Communications

PubMed ID: 41365859

Doi: 10.1038/s41467-025-65920-8

Gene-corrected regulatory T cell therapy for IL2RA deficiency

Authors: Alvin S Ha, Nechama Kalter, Michael Rosenberg, Luis A Acevedo, Brianna Liang, Weihong Liu, Sreenivasan Paruthiyil, Meenal Sinha, Alexander Vu, Vinh Nguyen, Zhongxia Qi, Netravathi Krishnappa, Jinna Shu, Jingwei Yu, Jason Catanzaro, Jeffrey A Bluestone, Qizhi Tang, Fyodor D Urnov, Alexander Marson, Ayal Hendel, Kevan C Herold, Brian R Shy, Jonathan H Esensten

Journal: Molecular Therapy

PubMed ID: 41376159

Doi: 10.1016/j.ymthe.2025.12.004

Products & Services: Molecular Biology Reagents

A broadly neutralizing antibody confers cross-genus protection against alphaherpesviruses by inhibiting gB-mediated membrane fusion

Authors: Guosong Wang, Yu Li, Chongxin Wu, Tian Chen, Mengxuan Gui, Yue Zeng, Hui Sun, Kaiyun Chen, Xiangfeng Xi, Yanbo Yang, Yuchen Jiang, Yanan Jiang, Liqin Liu, Chengyu Yang, Jiarui Xin, Caihong Liu, Yiyi Li, Ningning Huo, Yang Huang, Lina Lin, Hai Yu, Chenghao Huang, Quan Yuan, Shaowei Li, Kegong Tian, Qingbing Zheng, Ningshao Xia, Yixin Chen

Journal: Nature Communications

PubMed ID: 41402251

Doi: 10.1038/s41467-025-66099-8

Products & Services: Antibody Modification and Purification Services

Semisynthetic, Multicolor Probes for Bioluminescence Imaging

Authors: Suong Tran, Kat Usavage, Lila P Halbers, Claire Choplick, Grace Helton, Brenden Young, Jennifer A Prescher, Colin M Rathbun

Journal: ACS Omega

PubMed ID: 41427193

Doi: 10.1021.5c07587

Products & Services: Peptide Synthesis

Mutational analysis of Yih1 and IMPACT reveals amino acids required for Gcn2 inhibition

Authors: Bianca J M Sansom, Victoria J Gibbs, Anja H Schiemann, Evelyn Sattlegger

Journal: FEBS Letters

PubMed ID: 40862493

Doi: 10.1002/1873-3468.70148

Products & Services: Plasmid DNA Preparation

Going Retro, Going Viral: Experiences and Lessons in Drug Discovery from COVID-19

Authors: Bing Wang; Dmitri Svetlov; Dylan Bartikofsky; Christiane E. Wobus; Irina Artsimovitch

Journal: Molecules

PubMed ID: 35744940

Doi: 10.3390/molecules27123815

Going Retro, Going Viral: Experiences and Lessons in Drug Discovery from COVID-19

Authors: Bing Wang; Dmitri Svetlov; Dylan Bartikofsky; Christiane E. Wobus; Irina Artsimovitch

Journal: Molecules

PubMed ID: 35744940

Doi: 10.3390/molecules27123815

Going Retro, Going Viral: Experiences and Lessons in Drug Discovery from COVID-19

Authors: Bing Wang; Dmitri Svetlov; Dylan Bartikofsky; Christiane E. Wobus; Irina Artsimovitch

Journal: Molecules

PubMed ID: 35744940

Doi: 10.3390/molecules27123815

First inhibitor of a bacterial two-partner secretion system

Authors: Alfred Hartojo; Laurence Don Wai Luu; Lachlan Adamson; Kyra Majors; Ashleigh S. Paparella; Peggy A. Cotter; Richard M. Johnson; Matthew Thomas Doyle

Journal: biorxiv

PubMed ID: 41648283

Doi: 10.64898/2026.01.11.698920