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Engineered ipilimumab variants that bind human and mouse CTLA-4

Authors: Brett Robison 1, S J Diong 1, Anusha Kumar 1, Thomas M Moon , Olin Chang , Bryant Chau , Christine Bee , Ishita Barman , Arvind Rajpal , Alan J Korman , Sean West , Pavel Strop , Peter S Lee

Journal: MAbs

PubMed ID: 39849917

Doi: 10.1080/19420862.2025.2451296

Products & Services: Combinatorial DNA Libraries

Optimization of Multiple Combinations of Early Secretion Pathways to Enhance Extracellular Protein Secretion in Komagataella phaffii

Authors: Hai Xu, Shijie Wang, Kang Li, Zhonghu Bai, Yankun Yang

Journal: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

PubMed ID: 40616507

Doi: doi.org/10.1021/acs.jafc.5c03402

Products & Services: Gene Synthesis

An integrated electrochemical nanodevice for single-cell MiRNA-155 detection and drug evaluation

Authors: Zhuo Li , Zhaohan Wang , Jun Chen , Yafeng Wu

Journal: BIOSENSORS & BIOELECTRONICS

PubMed ID: 40695112

Doi: 10.1016/j.bios.2025.117804

Products & Services: PCR Cloning and Subcloning

Remolding Microenvironmental Homeostasis for Enhancing Regenerative Hypertrophic Scar Treatment Based on Functionalized Microneedles

Authors: Shengjie Jiang, Jialiang Zhou, Liyun Wang, Xin Liu, Jiaming Sun, Yu Zhuang, Li Yu, Haiyan Li, Dejian Li, Zhaoyong Zou, Zhen Gao, Kaili Lin

Journal: Interdisciplinary Materials

Doi: doi.org/10.1002/idm2.70000

Products & Services: Proteins, Expression, Isolation and Analysis

A Charge-Adhesive Targeted DNA Gel Bandage for the Precision Treatment of Inflammatory Bowel Disease

Authors: Peifen Lu, Hongxiu Yuan, Gang Wang, Tao Cheng, Lie Li, Yixi Dong, Runyu Zhao, Xuerui Zhang, Jianwei Jiao, Jin Jiao

Journal: Advanced Science

PubMed ID: 40685690

Doi: 10.1002/advs.202509419

Products & Services: Proteins, Expression, Isolation and Analysis

ZEB2 is a master switch controlling the tumor-associated macrophage program

Authors: Fadi Sheban, Truong San Phan, Ken Xie, Florian Ingelfinger, Chamutal Gur, Yuval Shapir Itai, Ronnie Blecher-Gonen, Chunsong Yu, Roberto Avellino, Paulina Chalan, Kiara Freitag, Ido Yofe, Vladimir Yutkin, Pierre Boyeau, Can Ergen, Justin Hong, Kfir Mazuz, Yuxiao Liu, Kangming Chen, Rony Dahan, Marcin Kortylewski, Nir Yosef, Assaf Weiner, Ido Amit

Journal: Cancer Cell

PubMed ID: 40215981

Doi: 10.1016/j.ccell.2025.03.021

Products & Services: Synthetic sgRNA and crRNA Service

Noninvasive Activation of Local and Systemic Immunity with a Sequential-Targeting Sonodynamic Nanovaccine to Treat Glioblastoma

Authors: Wei Cheng, Jiaojiao Yang, Yuqing Pan, Haijing Qu, Zhiran Duan, Jie Wu, Han Chen, Chao Wang, Xiangdong Xue

Journal: ACS Nano

PubMed ID: 40698543

Doi: 10.1021/acsnano.5c08928

Products & Services: Catalog Antibody

Single-cell RNA sequencing and PANDORA-seq reveal the pivotal role of piRNA in heat stress-induced testicular injury

Authors: Mailin Gan, Jianfeng Ma, Yuhang Lei, Yiting Yang, Yuheng Pan, Shuang Wu, Siyu Chen, Jiaxin Li, Linyuan Shen, Li Zhu