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Cofilin1-driven cytoskeletal remodeling modulates pan-cancer CD8 T cell immunotherapy responses

Authors: Le Li, Zheng Chao, Junbo Li, Chao Ma, Ren Zhang, Jie Zhang, Jing Luo, David Horne, Yanan Wang, Xiaodong Hao, Chunyu Zhang, Xiangdong Guo, Sheng Ma, Hao Peng, Zhiquan Hu, Bertram Yuh, Gong-Hong Wei, Xiangping Yang, Qiang Zhang, Baojun Wang, Xu Zhang, Zheng Liu, Zhihong Zhang, Peixiang Lan, Zhihua Wang

Journal: Cell Reports Medicine

PubMed ID: 42586064

Doi: 10.1016/j.xcrm.2026.102984

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DGAT1 Inhibition Induces Ferroptosis and Enhances Cancer Immunotherapy Efficacy

Authors: Dong Pan, Meng Jiao, Yanyan Zhu, Mengjie Hu, Fang Li, Jinming Yu, Chuan-Yuan Li

Journal: Cancer Research

PubMed ID: 41812065

Doi: 10.1158/0008-5472.CAN-25-0840

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αTIGIT-IL2 achieves tumor regression by promoting tumor-infiltrating regulatory T cell fragility in mouse models

Authors: Tianci Wang, Yupu Xu, Zhengfeng Zhang, Yaqi Wu, Long Chen, Xiaodong Zheng, Hui Peng, Qiang Zou, Rui Sun, Hongdi Ma, Haoyu Sun, Zhigang Tian & Xiaohu Zheng

Journal: Nature Communications

PubMed ID: 41107262

Doi: 10.1038/s41467-025-64296-z

ECSIT facilitates memory CD8+ T cell development by mediating fumarate synthesis during viral infection and tumorigenesis

Authors: Yongbing Yang , Yanan Wang , Zhongcheng Wang , Huanyu Yan , Yi Gong , Yingchao Hu , Yuying Jiang , Shuang Wen , Feifei Xu , Bingwei Wang , Fiachra Humphries , Yun Chen , Xi Wang , Shuo Yang

Journal: Nat Cell Biol .

PubMed ID: 38326554

Doi: 10.1038/s41556-024-01351-9

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RIG-I promotes immune evasion of colon cancer by modulating PD-L1 ubiquitination

Authors: Yangyang Zhang # 1, Lingxiu Zeng # 1, Meng Wang 1, Zhenwei Yang 1, Hailin Z 1, Liping Gao , Ranran Zhang , Jialong Liu , Wenqing Shan , Ying Chang ,Lan Liu , Qiu Zhao , Yong Li , Jing Liu

Journal: J Immunother Cancer .

PubMed ID: 37758653

Doi: 10.1136/jitc-2023-007313

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A genotype-phenotype screening system using conditionally immortalized immature dendritic cells

Authors: Liwei Zhao, Peng Liu, Wei Xie, Shuai Zhang, Sebastian Thieme, Laurence Zitvogel, Guido Kroemer, Oliver Kepp

Journal: STAR Protoc

PubMed ID: 34430908

Doi: 10.1016/j.xpro.2021.100732

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CD49a Regulates Cutaneous Resident Memory CD8⁺ T Cell Persistence and Response

Authors: Bromley SK, Akbaba H, Mani V, Mora-Buch R, Chasse AY, Sama A, Luster AD

Journal: Cell Reports

PubMed ID: 32877667

Doi: 10.1016/j.celrep.2020.108085

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Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells

Authors: Ruhland MK, Roberts EW, Cai E, Mujal AM, Marchuk K, Beppler C, Nam D, Serwas NK, Binnewies M, Krummel MF

Journal: Cancer Cell

PubMed ID: 32516589

Doi: 10.1016/j.ccell.2020.05.002

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Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response

Authors: Uribe-Herranz M1,2, Rafail S2, Beghi S1, Gil-de-Gómez L1, Verginadis I1, Bittinger K3, Pustylnikov S1, Pierini S1,2, Perales-Linares R1, Blair IA4, Mesaros CA4, Snyder NW5, Bushman F6, Koumenis C1, Facciabene A1,2.

Journal: J Clin Invest.

PubMed ID: 31815742

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Signaling through the Inhibitory Fc Receptor FcγRIIB Induces CD8+ T Cell Apoptosis to Limit T Cell Immunity.

Authors: Morris AB, Farley CR, Pinelli DF, Adams LE, Cragg MS, Boss JM, Scharer CD, Fribourg M, Cravedi P, Heeger PS, Ford ML.

Journal: Immunity

PubMed ID: 31940267

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