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RIG-I-Inducing Small Molecules Potently Inhibit HMA-Resistant AML Through Igniting the Overloaded dsRNA Arsenal

Authors: Xueqin Chen 1, Jiaqi Wu 1, Yuntong Li 1, Jiayu Huang 1, Xiangqin Weng 1, Jiale Wu 1, Shujun Xiao 1 2, Huaxin Song 1, Zhengyuan Wang 1, Ni Yan 1, Fangfang Shi 1, Derun Zheng 1 2, Kai Tan 1 2, Hesong Zhang 1, Jingyi Cui 1 2, Wen Wu 1, Wei Wu 3, Sujiang Zhang 1, Min Lu 1

Journal: Advanced Science

PubMed ID: 40568903

Doi: 10.1002/advs.202414477

Products & Services: Catalog Antibody

Inflammatory macrophage-derived itaconate inhibits DNA demethylase TET2 to prevent excessive osteoclast activation in rheumatoid arthritis

Authors: Kewei Rong, Dezheng Wang, Xiting Pu, Cheng Zhang, Pu Zhang, Xiankun Cao, Jinglin Zheng, Xiao Yang, Kexin Liu, Lei Shi, Yin Li, Peixiang Ma, Dan Ye, Jie Zhao, Pu Wang, An Qin

Journal: Bone Research

PubMed ID: 40500265

Doi: 10.1038/s41413-025-00437-w

Products & Services: Proteins, Expression, Isolation and Analysis

An Antioxidative and Active Shrinkage Hydrogel Integratedly Promotes Re-Epithelization and Skin Constriction for Enhancing Wound Closure

Authors: Jiacheng Sun, Wang Jia, Hedong Qi, Jiawei Huo, Xiaodan Liao, Yuan Xu, Jun Wang, Zihao Sun, Yang Liu, Jingchao Liu, Mingming Zhen, Chunru Wang, Chunli Bai

Journal: Adv Mater

PubMed ID: 38332741

Doi: 10.1002/adma.202312440

Products & Services: Proteins, Expression, Isolation and Analysis

A Novel Conserved Linear Neutralizing Epitope on the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein

Authors: Rong-Hong Hua, Shu-Jian Zhang, Bei Niu, Jin-Ying Ge, Ting Lan, Zhi-Gao Bu

Journal: Microbiol Spectr

PubMed ID: 37306579

Doi: 10.1128/spectrum.01190-23

Products & Services: Molecular Biology Reagents

Preparation and characterization of a fully human monoclonal antibody specific for human tumor necrosis factor alpha

Authors: Xinmei Liao, Hui Liang, Jian Pan, Qian Zhang, Jiaqi Niu, Cuili Xue, Jian Ni, Daxiang Cui

Journal: Bioengineered

PubMed ID: 34886761

Doi: 10.1080/21655979.2021.1967710

Products & Services: Proteins, Expression, Isolation and Analysis

Nitrosonisoldipine is a selective inhibitor of inflammatory caspases and protects against pyroptosis and related septic shock

Authors: Qianyue Chen, Jiashuo Zheng, Dingyu Wang, Qiyao Liu, Lulu Kang, Xiang Gao, Zhaoyu Lin

Journal: Eur J Immunol

PubMed ID: 33454984

Doi: 10.1002/eji.202048937

Products & Services: Molecular Biology Reagents

Magnesium protects against sepsis by blocking gasdermin D N-terminal-induced pyroptosis.

Authors: WangDingyu，ZhengJiashuo，HuQiongyuan，ZhaoCheng，ChenQianyue，ShiPeiliang，ChenQin，ZouYujie，ZouDayuan，LiuQiyao，PeiJingwen，WuXiuwen，GaoXiang，RenJianan，LinZh

Journal: Cell Death Differ.

PubMed ID: 31209359

Doi: 10.1038/s41418-019-0366-x

Products & Services: Proteins, Expression, Isolation and Analysis

Using the novel HiBiT tag to label cell surface relaxin receptors for BRET proximity analysis.

Authors: HoareBradley L，KocanMartina，BruellShoni，ScottDaniel J，BathgateRoss

Journal: Pharmacol Res Perspect

PubMed ID: 31384473

Doi: 10.1002/prp2.513

Products & Services: Proteins, Expression, Isolation and Analysis

Translational Regulation of Non-autonomous Mitochondrial Stress Response Promotes Longevity.

Authors: LanJianfeng，RollinsJarod A，ZangXiao，WuDi，ZouLina，WangZi，YeChang，WuZixing，KapahiPankaj，RogersAric N，Ch