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Target Identification of an Antimalarial Oxaborole Identifies AN13762 as an Alternative Chemotype for Targeting CPSF3 in Apicomplexan Parasites

Authors: Valeria Bellini , Christopher Swale , Marie-Pierre Brenier-Pinchart , Tiffany Pezier , Sonia Georgeault , Fabrice Laurent , Mohamed-Ali Hakimi , Alexandre Bougdour

Journal: iScience

PubMed ID: 33336164

Doi: 10.1016/j.isci.2020.101871

Products & Services: Gene Synthesis

Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection

Authors: Christopher Swale , Alexandre Bougdour , Audrey Gnahoui-David , Julie Tottey , Sonia Georgeault , Fabrice Laurent , Andrés Palencia , Mohamed-Ali Hakimi

Journal: Sci Transl Med

PubMed ID: 31694928

Doi: 10.1126/scitranslmed.aax7161

Products & Services: Gene Synthesis

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