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Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350

Authors: M Gordon Joyce, Wei Bu, Wei-Hung Chen, Rebecca A Gillespie, Sarah F Andrews, Adam K Wheatley, Yaroslav Tsybovsky, Jaime L Jensen, Tyler Stephens, Madhu Prabhakaran, Brian E Fisher, Sandeep R Narpala, Meghna Bagchi, Adrian B McDermott, Gary J Nabel, Peter D Kwong, John R Mascola, Jeffrey I Cohen, Masaru Kanekiyo

Journal: Immunity

PubMed ID: 39909035

Doi: 10.1016/j.immuni.2025.01.010

Products & Services: Recombinant Antibody Expression

Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates

Authors: Prakash Jadhav, Xueying Liang, Ahmadullah Ansari, Bin Tan, Haozhou Tan, Kan Li, Xiang Chi, Alexandra Ford, Francesc Xavier Ruiz, Eddy Arnold, Xufang Deng, Jun Wang

Journal: Nature Communications

PubMed ID: 39948104

Doi: 10.1038/s41467-025-56902-x

Products & Services: Codon Optimization

Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling

Authors: Jeonghyeon Kwon, Haruya Kawase, Kenny Mattonet, Stefan Guenther, Lisa Hahnefeld, Jamal Shamsara, Jan Heering, Michael Kurz, Sina Kirchhofer, Cornelius Krasel, Michaela Ulrich, Margherita Persechino, Sripriya Murthy, Cesare Orlandi, Christian D Sadik, Gerd Geisslinger, Moritz Bünemann, Peter Kolb, Stefan Offermanns, Nina Wettschureck

Journal: Nature Communications

PubMed ID: 39920161

Doi: 10.1038/s41467-025-56713-0

Products & Services: Peptide Synthesis

Massively parallel variant-to-function mapping determines functional regulatory variants of non-small cell lung cancer

Authors: Congcong Chen, Yang Li, Yayun Gu, Qiqi Zhai, Songwei Guo, Jun Xiang, Yuan Xie, Mingxing An, Chenmeijie Li, Na Qin, Yanan Shi, Liu Yang, Jun Zhou, Xianfeng Xu, Ziye Xu, Kai Wang, Meng Zhu, Yue Jiang, Yuanlin He, Jing Xu, Rong Yin, Liang Chen, Lin Xu, Juncheng Dai, Guangfu Jin, Zhibin Hu, Cheng Wang, Hongxia Ma, Hongbing Shen

Journal: Nature Communications

PubMed ID: 39910069

Doi: 10.1038/s41467-025-56725-w

Products & Services: Gene Synthesis

Nucleotide-induced hyper-oligomerization inactivates transcription termination factor ρ

Authors: Bing Wang, Nelly Said, Tarek Hilal, Mark Finazzo, Markus C Wahl, Irina Artsimovitch

Journal: Nature Communications

PubMed ID: 39952913

Doi: 10.1038/s41467-025-56824-8

Products & Services: Protein Electrophoresis and Western

Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses

Authors: Cheng-Bao Ma, Chen Liu, Young-Jun Park, Jingjing Tang, Jing Chen, Qing Xiong, Jimin Lee, Cameron Stewart, Daniel Asarnow, Jack Brown, M Alejandra Tortorici, Xiao Yang, Ye-Hui Sun, Yuan-Mei Chen, Xiao Yu, Jun-Yu Si, Peng Liu, Fei Tong, Mei-Ling Huang, Jing Li, Zheng-Li Shi, Zengqin Deng, David Veesler, Huan Yan

Journal: Cell

PubMed ID: 39922191

Doi: 10.1016/j.cell.2024.12.031

Products & Services: Codon Optimization

The CXCL8/MAPK/hnRNP-K axis enables susceptibility to infection by EV-D68, rhinovirus, and influenza virus in vitro

Authors: Qingran Yang, Haoran Guo, Huili Li, Zhaoxue Li, Fushun Ni, Zhongmei Wen, Kai Liu, Huihui Kong, Wei Wei

Journal: Nature Communications

PubMed ID: 39962077

Doi: 10.1038/s41467-025-57094-0

Products & Services: Catalog Antibodies

Polyamine-Depleting Hydrogen-Bond Organic Frameworks Unleash Dendritic Cell and T Cell Vigor for Targeted CRISPR/Cas-Assisted Cancer Immunotherapy

Authors: Yongchun Pan, Fei Zeng, Xiaowei Luan, Guanzhong He, Shurong Qin, Qianglan Lu, Bangshun He, Xin Han, Yujun Song