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Reconstitution of human CMG helicase ubiquitylation by CUL2LRR1 and multiple E2 enzymes

Authors: Thanh Thi Le, Johanna Ainsworth, Cristian Polo Rivera, Thomas Macartney, Karim P M Labib

Journal: Biochem J

PubMed ID: 34195792

Doi: 10.1042/BCJ20210315

Products & Services: Mammalian Expression

Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine

Authors: Kelly L Hawley, Jairo M Montezuma-Rusca, Kristina N Delgado, Navreeta Singh, Vladimir N Uversky, Melissa J Caimano, Justin D Radolf, Amit Luthra

Journal: J Bacteriol

PubMed ID: 33972353

Doi: 10.1128/JB.00082-21

Products & Services: Codon Optimization

Chemerin/ChemR23 signaling mediates the effects of ultra-high molecular weight polyethylene wear particles on the balance between osteoblast and osteoclast differentiation

Authors: Fengchao Zhao, Dingwei Cang, Jianzhi Zhang, Li Zheng

Journal: Ann Transl Med

PubMed ID: 34430590

Doi: 10.21037/atm-21-2945

Products & Services: Molecular Biology Reagents

Immunogenicity Studies of Plant-Produced SARS-CoV-2 Receptor Binding Domain-Based Subunit Vaccine Candidate with Different Adjuvant Formulations

Authors: Konlavat Siriwattananon, Suwimon Manopwisedjaroen, Balamurugan Shanmugaraj, Eakachai Prompetchara, Chutitorn Ketloy, Supranee Buranapraditkun, Kittipan Tharakhet, Papatsara Kaewpang, Kiat Ruxrungtham, Arunee Thitithanyanont, Waranyoo Phoolcharoen

Journal: Vaccines (Basel)

PubMed ID: 34358160

Doi: 10.3390/vaccines9070744

Products & Services: Serology SARS-Cov-2 detection kits

Lipopolysaccharide Binding Protein and CD14, Cofactors of Toll-like Receptors, Are Essential for Low-Grade Inflammation-Induced Exacerbation of Cartilage Damage in Mouse Models of Posttraumatic Osteoarthritis

Authors: Yoonkyung Won, Jeong-In Yang, Seulki Park, Jang-Soo Chun

Journal: Arthritis Rheumatol

PubMed ID: 33559324

Doi: 10.1002/art.41679

Products & Services: Recombinant Proteins

Interferon-beta, interferon-gamma and their fusion interferon of Siberian tigers (Panthera tigris altaica) in China are involved in positive-feedback regulation of interferon production

Authors: Mengyao Mu, Hongjing Zhao, Yu Wang, Menghao Guo, Xiaopan Nie, Yachen Liu, Mingwei Xing

Journal: Dev Comp Immunol

PubMed ID: 34329648

Doi: 10.1016/j.dci.2021.104211

Products & Services: Recombinant Antibody Expression

RNase κ promotes robust piRNA production by generating 2',3'-cyclic phosphate-containing precursors

Authors: Megumi Shigematsu, Takuya Kawamura, Keisuke Morichika, Natsuko Izumi, Takashi Kiuchi, Shozo Honda, Venetia Pliatsika, Ryuma Matsubara, Isidore Rigoutsos, Susumu Katsuma, Yukihide Tomari, Yohei Kirino

Journal: Nat Commun

PubMed ID: 34301931

Doi: 10.1038/s41467-021-24681-w

Products & Services: Recombinant Antibody Expression

Cryo-EM structure of human Wntless in complex with Wnt3a

Authors: Qing Zhong, Yanyu Zhao, Fangfei Ye, Zaiyu Xiao, Gaoxingyu Huang, Meng Xu, Yuanyuan Zhang, Xiechao Zhan, Ke Sun, Zhizhi Wang, Shanshan Cheng, Shan Feng, Xiuxiu Zhao, Jizhong Zhang, Peilong Lu, Wenqing Xu, Qiang Zhou, Dan Ma

Journal: Nat Commun

PubMed ID: 34315898

Doi: 10.1038/s41467-021-24731-3

Products & Services: Protein and Antibody Isolation

Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2

Authors: Qi Zhang, Bin Ju, Jiwan Ge, Jasper Fuk-Woo Chan, Lin Cheng, Ruoke Wang, Weijin Huang, Mengqi Fang, Peng Chen, Bing Zhou, Shuo Song, Sisi Shan, Baohua Yan, Senyan Zhang, Xiangyang Ge, Jiazhen Yu, Juanjuan Zhao, Haiyan Wang, Li Liu, Qining Lv, Lili Fu, Xuanling Shi, Kwok Yung Yuen, Lei Liu, Youchun Wang, Zhiwei Chen, Linqi Zhang, Xinquan Wang, Zheng Zhang

Journal: Nat Commun

PubMed ID: 34244522

Doi: 10.1038/s41467-021-24514-w

Products & Services: Protein and Antibody Isolation

Fine-tuning the expression of pathway gene in yeast using a regulatory library formed by fusing a synthetic minimal promoter with different Kozak variants

Authors: Liping Xu, Pingping Liu, Zhubo Dai, Feiyu Fan, Xueli Zhang

Journal: Microb Cell Fact

PubMed ID: 34320991

Doi: 10.1186/s12934-021-01641-z

Products & Services: Plasmid DNA Preparation