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miR-29a, b, and c regulate SLC5A8 expression in intestinal epithelial cells
Authors: Arivarasu N Anbazhagan, Shubha Priyamvada, Anoop Kumar, Dulari Jayawardena, Alip Borthakur, Seema Saksena, Ravinder K Gill, Waddah A Alrefai, Pradeep K Dudeja
Journal: Am J Physiol Gastrointest Liver Physiol
PubMed ID: 34231393
Doi: 10.1152/ajpgi.00148.2021
Products & Services: Custom Vector Construction   
Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
Authors: Sebastian M Dieter, Christine Siegl, Paula L Codó, Mario Huerta, Anna L Ostermann-Parucha, Erik Schulz, Martina K Zowada, Sylvia Martin, Karin Laaber, Ali Nowrouzi, Mona Blatter, Sina Kreth, Frank Westermann, Axel Benner, Ulrike Uhrig, Kerstin Putzker, Joe Lewis, Andrea Haegebarth, Dominik Mumberg, Simon J Holton, Joerg Weiske, Lena-Marit Toepper, Ulrike Scheib, Gerhard Siemeister, Claudia R Ball, Bernhard Kuster, Gabriele Stoehr, Hannes Hahne, Sarah Johannes, Martin Lange, Friederike Herbst, Hanno Glimm
Journal: Cell Rep
PubMed ID: 34289372
Doi: 10.1016/j.celrep.2021.109394
Products & Services: Mammalian Expression   
Alternative 3' UTRs play a widespread role in translation-independent mRNA association with the endoplasmic reticulum
Authors: Larry C Cheng, Dinghai Zheng, Qiang Zhang, Aysegul Guvenek, Hong Cheng, Bin Tian
Journal: Cell Rep
PubMed ID: 34289366
Doi: 10.1016/j.celrep.2021.109407
Products & Services: PCR and Cloning   
Trimetazidine attenuates dexamethasone-induced muscle atrophy via inhibiting NLRP3/GSDMD pathway-mediated pyroptosis
Authors: Li Wang, Xin-Feng Jiao, Cheng Wu, Xiao-Qing Li, Hui-Xian Sun, Xi-Yu Shen, Kang-Zhen Zhang, Can Zhao, Li Liu, Man Wang, Yun-Ling Bu, Jia-Wen Li, Fan Xu, Chen-Lu Chang,Xiang Lu,corresponding author and Wei Gaocorresponding author
Journal: Journal List
PubMed ID: 34537816
Doi: 10.1038/s41420-021-00648-0
Products & Services: Proteins, Expression, Isolation and Analysis   
Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes
Authors: Benjamin J Eduful, Sean N O'Byrne, Louisa Temme, Christopher R M Asquith, Yi Liang, Alfredo Picado, Joseph R Pilotte, Mohammad Anwar Hossain, Carrow I Wells, William J Zuercher, Carolina M C Catta-Preta, Priscila Zonzini Ramos, André de S Santiago, Rafael M Couñago, Christopher G Langendorf, Kévin Nay, Jonathan S Oakhill, Thomas L Pulliam, Chenchu Lin, Dominik Awad, Timothy M Willson, Daniel E Frigo, John W Scott, David H Drewry
Journal: J Med Chem
PubMed ID: 34264658
Doi: 10.1021/acs.jmedchem.0c02274
Products & Services: Stable Cell Lines   
Heparin promotes fibrillation of most phenol-soluble modulin virulence peptides from Staphylococcus aureus
Authors: Zahra Najarzadeh, Masihuz Zaman, Vita Sereikaite, Kristian Strømgaard, Maria Andreasen, Daniel E Otzen
Journal: J Biol Chem
PubMed ID: 34270957
Doi: 10.1016/j.jbc.2021.100953
Products & Services: Catalog Peptides   
Folding of cohesin's coiled coil is important for Scc2/4-induced association with chromosomes
Authors: Naomi J Petela, Andres Gonzalez Llamazares, Sarah Dixon, Bin Hu, Byung-Gil Lee, Jean Metson, Heekyo Seo, Antonio Ferrer-Harding, Menelaos Voulgaris, Thomas Gligoris, James Collier, Byung-Ha Oh, Jan Löwe, Kim A Nasmyth
Journal: Elife
PubMed ID: 34259632
Doi: 10.7554/eLife.67268
Products & Services: Catalog Antibody   
spp Omp25 Promotes Proteasome-Mediated cGAS Degradation to Attenuate IFN-β Production
Authors: Ruizhen Li, Wenli Liu, Xiangrui Yin, Fangfang Zheng, Zhenyu Wang, Xingchen Wu, Xiaohua Zhang, Qian Du, Yong Huang, Dewen Tong
Journal: Front Microbiol
PubMed ID: 34394047
Doi: 10.3389/fmicb.2021.702881
Products & Services: Catalog Antibody   
A Covalent Calmodulin Inhibitor as a Tool to Study Cellular Mechanisms of K-Ras-Driven Stemness
Authors: Sunday Okutachi, Ganesh Babu Manoharan, Alexandros Kiriazis, Christina Laurini, Marie Catillon, Frank McCormick, Jari Yli-Kauhaluoma, Daniel Abankwa
Journal: Front Cell Dev Biol
PubMed ID: 34307350
Doi: 10.3389/fcell.2021.665673
Products & Services: Catalog Peptides   
Measuring nonhomologous end-joining, homologous recombination and alternative end-joining simultaneously at an endogenous locus in any transfectable human cell
Authors: Suleman S Hussain, Rahul Majumdar, Grace M Moore, Himanshi Narang, Erika S Buechelmaier, Maximilian J Bazil, Pavithran T Ravindran, Jonathan E Leeman, Yi Li, Manisha Jalan, Kyrie S Anderson, Andrea Farina, Rekha Soni, Neeman Mohibullah, Edin Hamzic, Xiaoqing Rong-Mullins, Christopher Sifuentes, Rama R Damerla, Agnes Viale, Simon N Powell, Daniel S Higginson
Journal: Nucleic Acids Res
PubMed ID: 33877327
Doi: 10.1093/nar/gkab262
Products & Services: Plasmid DNA Preparation   

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