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Integrative multi-omics profiling reveals cAMP-independent mechanisms regulating hyphal morphogenesis in Candida albicans

Authors: Kyunghun Min, Thomas F Jannace, Haoyu Si, Krishna R Veeramah, John D Haley, James B Konopka

Journal: PLoS Pathog

PubMed ID: 34398936

Doi: 10.1371/journal.ppat.1009861

Products & Services: Polyclonal Antibody Services

FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease

Authors: Robert Goold, Joseph Hamilton, Thomas Menneteau, Michael Flower, Emma L Bunting, Sarah G Aldous, Antonio Porro, José R Vicente, Nicholas D Allen, Hilary Wilkinson, Gillian P Bates, Alessandro A Sartori, Konstantinos Thalassinos, Gabriel Balmus, Sarah J Tabrizi

Journal: Cell Rep

PubMed ID: 34469738

Doi: 10.1016/j.celrep.2021.109649

Products & Services: Mutant Libraries

Ganoderic Acid A-Mediated Modulation of Microglial Polarization is Involved in Depressive-Like Behaviors and Neuroinflammation in a Rat Model of Post-Stroke Depression

Authors: Ling Zhang, Lei Zhang, Rubo Sui

Journal: Neuropsychiatr Dis Treat

PubMed ID: 34421302

Doi: 10.2147/NDT.S317207

Products & Services: Custom DNA/RNA Oligos

Digestive Enzyme Activity and Protein Degradation in Plasma of Heart Failure Patients

Authors: Vasiliki Courelli, Alla Ahmad, Majid Ghassemian, Chris Pruitt, Paul J Mills, Geert W Schmid-Schönbein

Journal: Cell Mol Bioeng

PubMed ID: 34900012

Doi: 10.1007/s12195-021-00693-w

Products & Services: Catalog Antibodies

Blockade of Autocrine CCL5 Responses Inhibits Zika Virus Persistence and Spread in Human Brain Microvascular Endothelial Cells

Authors: Megan C Mladinich, Jonas N Conde, William R Schutt, Sook-Young Sohn, Erich R Mackow

Journal: MBio

PubMed ID: 34399621

Doi: 10.1128/mBio.01962-21

Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers

Authors: Khuraijam Dhanachandra Singh, Zaira P Jara, Terri Harford, Prasenjit Prasad Saha, Triveni R Pardhi, Russell Desnoyer, Sadashiva S Karnik

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34380734

Doi: 10.1073/pnas.2019126118

Products & Services: Mutant Libraries

Secondary Structure of Human Evolved Gene Product NCYM Analyzed by Vacuum-Ultraviolet Circular Dichroism

Authors: Tatsuhito Matsuo, Kazuma Nakatani, Taiki Setoguchi, Koichi Matsuo, Taro Tamada, Yusuke Suenaga

Journal: Front Oncol

PubMed ID: 34497756

Doi: 10.3389/fonc.2021.688852

Products & Services: Plasmid DNA Preparation

The Role of Hexokinase and Hexose Transporters in Preferential Use of Glucose over Fructose and Downstream Metabolic Pathways in the Yeast

Authors: Piotr Hapeta, Patrycja Szczepańska, Tadeusz Witkowski, Jean-Marc Nicaud, Anne-Marie Crutz-Le Coq, Zbigniew Lazar

Journal: Int J Mol Sci

PubMed ID: 34502217

Doi: 10.3390/ijms22179282

Products & Services: Codon Optimization

CRISPR-Cas9-mediated reactivation of the uricase pseudogene in human cells prevents acute hyperuricemia

Authors: Lais de Lima Balico, Eric A Gaucher

Journal: Mol Ther Nucleic Acids

PubMed ID: 34589279

Doi: 10.1016/j.omtn.2021.08.002

Products & Services: Mammalian Expression

Vesicular Stomatitis Virus Chimeras Expressing the Oropouche Virus Glycoproteins Elicit Protective Immune Responses in Mice

Authors: Sarah Hulsey Stubbs, Marjorie Cornejo Pontelli, Nischay Mishra, Changhong Zhou, Juliano de Paula Souza, Rosa Maria Mendes Viana, W Ian Lipkin, David M Knipe, Eurico Arruda, Sean P J Whelan

Journal: MBio

PubMed ID: 34340542

Doi: 10.1128/mBio.00463-21

Products & Services: Mammalian Expression