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Synthetic antibacterial discovery of symbah-1, a macrocyclic β-hairpin peptide antibiotic

Authors: Justin R Randall, Gillian Davidson, Renee M Fleeman, Santos A Acosta, Ian M Riddington, T Jeffrey Cole, Cory D DuPai, Bryan W Davies

Journal: iScience

PubMed ID: 35005555

Doi: 10.1016/j.isci.2021.103611

Products & Services: Peptide Synthesis

Mechanistic Insights into the Preference for Tandem Binding Sites in DNA Recognition by FOXM1

Authors: Huajun Zhang, Shuyan Dai, Xujun Liang, Jun Li, Yongheng Chen

Journal: J Mol Biol

PubMed ID: 34973238

Doi: 10.1016/j.jmb.2021.167426

Products & Services: Custom DNA/RNA Oligos

Functional conservation and divergence of the helix-turn-helix motif of E2 ubiquitin-conjugating enzymes

Authors: Kaeli A Welsh, Derek L Bolhuis, Anneroos E Nederstigt, Joshua Boyer, Brenda R S Temple, Thomas Bonacci, Li Gu, Alban Ordureau, J Wade Harper, Joshua P Steimel, Qi Zhang, Michael J Emanuele, Joseph S Harrison, Nicholas G Brown

Journal: EMBO J

PubMed ID: 34942047

Doi: 10.15252/embj.2021108823

Products & Services: Protein and Antibody Isolation

A single injection of CM1021, a long half-life hepatocyte growth factor mimetic, increases liver mass in mice

Authors:

Journal: Biochem Biophys Rep

PubMed ID: 34977363

Doi: 10.1016/j.bbrep.2021.101186

Products & Services: Plasmid DNA Preparation

Design of Mimetic Antibodies Targeting the SARS-CoV-2 Spike Glycoprotein Based on the GB1 Domain: A Molecular Simulation and Experimental Study

Authors: Anderson A. E Santo; Aline Reis; Anderson A. Pinheiro; Paulo I. da Costa; Gustavo T. Feliciano

Journal: Biochemistry

PubMed ID: 40096593

Doi: 10.1021/acs.biochem.4c00671

Cloning and Characterization of Two Putative P-Type ATPases from the Marine Microalga Similar to Plant H-ATPases and Their Gene Expression Analysis under Conditions of Hyperosmotic Salt Shock

Authors: Dmitrii A Matalin, Dmitrii E Khramov, Alexey V Shuvalov, Vadim S Volkov, Yurii V Balnokin, Larissa G Popova

Journal: Plants (Basel)

PubMed ID: 34961138

Doi: 10.3390/plants10122667

Products & Services: Protein Tools

Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity

Authors: Zhenghai Tang, Dominique Davidson, Rui Li, Ming-Chao Zhong, Jin Qian, Jun Chen, André Veillette

Journal: Cell Rep

PubMed ID: 34910922

Doi: 10.1016/j.celrep.2021.110111

Products & Services: Custom Vector Construction

The protective effects of S14G-humanin (HNG) against lipopolysaccharide (LPS)- induced inflammatory response in human dental pulp cells (hDPCs) mediated by the TLR4/MyD88/NF-κB pathway

Authors: Ping Zhang, Zhiqiang Cui, Shuai Li

Journal: Bioengineered

PubMed ID: 34605740

Doi: 10.1080/21655979.2021.1979914

Products & Services: Mammalian Expression

Cabergoline possesses a beneficial effect on blood-brain barrier (BBB) integrity against lipopolysaccharide (LPS)

Authors: Lina You, Haidong Jiang

Journal: Bioengineered

PubMed ID: 34592907

Doi: 10.1080/21655979.2021.1987066

Products & Services: Plasmid DNA Preparation

ER proteins decipher the tubulin code to regulate organelle distribution

Authors: Pengli Zheng, Christopher J Obara, Ewa Szczesna, Jonathon Nixon-Abell, Kishore K Mahalingan, Antonina Roll-Mecak, Jennifer Lippincott-Schwartz, Craig Blackstone

Journal: Nature

PubMed ID: 34912111

Doi: 10.1038/s41586-021-04204-9

Products & Services: Mutant Libraries