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Vulnerable exons, like ACADM exon 5, are highly dependent on maintaining a correct balance between splicing enhancers and silencers

Authors: Lise L Holm, Thomas K Doktor, Michael B Hansen, Ulrika S S Petersen, Brage S Andresen

Journal: Hum Mutat

PubMed ID: 34923709

Doi: 10.1002/humu.24321

Products & Services: Mutagenesis Services

Critical residues for proteolysis activity of maize chlorotic dwarf virus (MCDV) 3C-like protease and comparison of activity of orthologous waikavirus proteases

Authors: Lucy R Stewart, Matthew Willman, DeeMarie Marty, Anna Emmick Cole, Kristen Willie

Journal: Virology

PubMed ID: 34998226

Doi: 10.1016/j.virol.2021.12.008

Products & Services: Gene Synthesis

BIX-01294 enhances the effect of chemotherapy on colorectal cancer by inhibiting the expression of stemness genes

Authors: Shikang Liu, Yihang Jiang, Hua Yang, Zhongke Hua, Yu Han, Cai Zhou, Shuling Xu, Shenglan Nie, Gaixia Xu, Xingsheng Shu, Xiaomei Wang

Journal: Biochem Biophys Res Commun

PubMed ID: 34979318

Doi: 10.1016/j.bbrc.2021.12.089

Products & Services: Recombinant Proteins

Targeting cIAPs attenuates CCl-induced liver fibrosis by increasing MMP9 expression derived from neutrophils

Authors: Yi Wu, Suwen Lu, Xuan Huang, Yuanyuan Liu, Kuiyuan Huang, Ziying Liu, Weikang Xu, Wei Zhu, Jinlin Hou, Hongyan Liu, Xiaoyong Zhang

Journal: Life Sci

PubMed ID: 34914932

Doi: 10.1016/j.lfs.2021.120235

Products & Services: Catalog Peptides

hsa_circ_0003410 promotes hepatocellular carcinoma progression by increasing the ratio of M2/M1 macrophages through the miR-139-3p/CCL5 axis

Authors: Pei Cao, Bo Ma, Ding Sun, Weigang Zhang, Junyi Qiu, Lei Qin, Xiaofeng Xue

Journal: Cancer Sci

PubMed ID: 34890089

Doi: 10.1111/cas.15238

Products & Services: Mammalian Expression

T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes

Authors: Muhammad Ali, Eirini Giannakopoulou, Yingqian Li, Madeleine Lehander, Stina Virding Culleton, Weiwen Yang, Cathrine Knetter, Mete Can Odabasi, Ravi Chand Bollineni, Xinbo Yang, Zsofia Foldvari, Maxi-Lu Böschen, Eli Taraldsrud, Erlend Strønen, Mireille Toebes, Amy Hillen, Stefania Mazzi, Arnoud H de Ru, George M C Janssen, Arne Kolstad, Geir Erland Tjønnfjord, Benedicte A Lie, Marieke Griffioen, Sören Lehmann, Liv Toril Osnes, Jochen Buechner, K Christopher Garcia, Ton N Schumacher, Peter A van Veelen, Matthias Leisegang, Sten Eirik W Jacobsen, Petter Woll, Johanna Olweus

Journal: Nat Biotechno.

PubMed ID: 34873326

Doi: 10.1038/s41587-021-01089-x

Products & Services: Codon Optimization

Increased SERPINA3 Level Is Associated with Ulcerative Colitis

Authors: Jingwei Zhang, Wei Wang, Shenglong Zhu, Yongquan Chen

Journal: Diagnostics (Basel)

PubMed ID: 34943607

Doi: 10.3390/diagnostics11122371

Products & Services: Recombinant Proteins

Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice

Authors: Jamilah Abusarah, Fatemeh Khodayarian, Nehme El-Hachem, Natasha Salame, Martin Olivier, Mohammad Balood, Katiane Roversi, Sebastien Talbot, Jean-Pierre Bikorimana, Jingkui Chen, Mario Jolicoeur, Louis-Eric Trudeau, Samaneh Kamyabiazar, Borhane Annabi, Francis Robert, Jerry Pelletier, Abed-El-Hakim El-Kadiry, Riam Shammaa, and Moutih Rafe

Journal: Cell Reports Medicine

PubMed ID: 35028603

Doi: 10.1016/j.xcrm.2021.100455

Products & Services: Peptide Synthesis

An easy method for developing fusion enabled SARS-CoV2 virus fusion mimic (SCFM), bypassing the need of Bio Safety Level (BSL) facility

Authors: Abhishek Das, Satarupa Dutta, Dewanshu Sharma, Amit Pal, Nirmalya Ganguli, Subeer S Majumdar

Journal: Bioengineered

PubMed ID: 34436976

Doi: 10.1080/21655979.2021.1955509

Products & Services: PCR Cloning and Subcloning

Long non-coding RNA NBR2 suppresses the progress of colorectal cancer in vitro and in vivo by regulating the polarization of TAM

Authors: Fuji Lai, Huiqin Zhang, Binbin Xu, Yangyang Xie, Hua Yu

Journal: Bioengineered

PubMed ID: 34506209

Doi: 10.1080/21655979.2021.1958558

Products & Services: Molecular Biology Reagents