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Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers

Authors: Khuraijam Dhanachandra Singh, Zaira P Jara, Terri Harford, Prasenjit Prasad Saha, Triveni R Pardhi, Russell Desnoyer, Sadashiva S Karnik

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34380734

Doi: 10.1073/pnas.2019126118

Products & Services: Mutant Libraries

Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern

Authors: Wenwei Li, Yaozong Chen, Jérémie Prévost, Irfan Ullah, Maolin Lu, Shang Yu Gong, Alexandra Tauzin, Romain Gasser, Dani Vézina, Sai Priya Anand, Guillaume Goyette, Debashree Chaterjee, Shilei Ding, William D Tolbert, Michael W Grunst, Yuxia Bo, Shijian Zhang, Jonathan Richard, Fei Zhou, Rick K Huang, Lothar Esser, Allison Zeher, Marceline Côté, Priti Kumar, Joseph Sodroski, Di Xia, Pradeep D Uchil, Marzena Pazgier, Andrés Finzi, Walther Mothes

Journal: biorxiv

PubMed ID: 34373853

Doi: 10.1101/2021.08.02.454546

Products & Services: Codon Optimization

CRISPR-Cas9-mediated reactivation of the uricase pseudogene in human cells prevents acute hyperuricemia

Authors: Lais de Lima Balico, Eric A Gaucher

Journal: Mol Ther Nucleic Acids

PubMed ID: 34589279

Doi: 10.1016/j.omtn.2021.08.002

Products & Services: Mammalian Expression

Blockade of Autocrine CCL5 Responses Inhibits Zika Virus Persistence and Spread in Human Brain Microvascular Endothelial Cells

Authors: Megan C Mladinich, Jonas N Conde, William R Schutt, Sook-Young Sohn, Erich R Mackow

Journal: MBio

PubMed ID: 34399621

Doi: 10.1128/mBio.01962-21

The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output

Authors: Dimitris C Kanellis, Jaime A Espinoza, Asimina Zisi, Elpidoforos Sakkas, Jirina Bartkova, Anna-Maria Katsori, Johan Boström, Lars Dyrskjøt, Helle Broholm, Mikael Altun, Simon J Elsässer, Mikael S Lindström, Jiri Bartek

Journal: Sci Adv

PubMed ID: 34348895

Doi: 10.1126/sciadv.abf7561

Products & Services: Plasmid DNA Preparation

Multiple epitopes of hepatitis B virus surface antigen targeted by human plasma-derived immunoglobulins coincide with clinically observed escape mutations

Authors: Sreya Tarafdar, Maria Luisa Virata, Hailing Yan, Lilin Zhong, Lu Deng, Yanqun Xu, Yong He, Evi Struble, Pei Zhang

Journal: J Med Virol

PubMed ID: 34406663

Doi: 10.1002/jmv.27278

Products & Services: Peptide Synthesis

Complete and efficient conversion of plant cell wall hemicellulose into high-value bioproducts by engineered yeast

Authors: Liang Sun, Jae Won Lee, Sangdo Yook, Stephan Lane, Ziqiao Sun, Soo Rin Kim, Yong-Su Jin

Journal: Nat Commun

PubMed ID: 34404791

Doi: 10.1038/s41467-021-25241-y

Products & Services: PCR Cloning and Subcloning

The Use of CRISPR/Cas9 as a Tool to Study Human Infectious Viruses

Authors: Huafeng Lin, Gang Li, Xiangwen Peng, Aimin Deng, Lei Ye, Lei Shi, Tuanmei Wang, Jun He

Journal: Front Cell Infect Microbiol

PubMed ID: 34513721

Doi: 10.3389/fcimb.2021.590989

Digestive Enzyme Activity and Protein Degradation in Plasma of Heart Failure Patients

Authors: Vasiliki Courelli, Alla Ahmad, Majid Ghassemian, Chris Pruitt, Paul J Mills, Geert W Schmid-Schönbein

Journal: Cell Mol Bioeng

PubMed ID: 34900012

Doi: 10.1007/s12195-021-00693-w

Products & Services: Catalog Antibody

Identification and in-silico characterization of taxadien-5α-ol-O-acetyltransferase (TDAT) gene in Corylus avellana L

Authors: Mona Raeispour Shirazi, Sara Alsadat Rahpeyma, Sajad Rashidi Monfared, Jafar Zolala, Azadeh Lohrasbi-Nejad

Journal: PLoS ONE

PubMed ID: 34449796

Doi: 10.1371/journal.pone.0256704

Products & Services: Protein Tools

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