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Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes

Authors: Erika Casari, Elisa Gobbini, Marco Gnugnoli, Marco Mangiagalli, Michela Clerici, Maria Pia Longhese

Journal: Nat Commun

PubMed ID: 34362907

Doi: 10.1038/s41467-021-25090-9

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Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM

Authors: Aleksandar Antanasijevic, Leigh M Sewall, Christopher A Cottrell, Diane G Carnathan, Luis E Jimenez, Julia T Ngo, Jennifer B Silverman, Bettina Groschel, Erik Georgeson, Jinal Bhiman, Raiza Bastidas, Celia LaBranche, Joel D Allen, Jeffrey Copps, Hailee R Perrett, Kimmo Rantalainen, Fabien Cannac, Yuhe R Yang, Alba Torrents de la Peña, Rebeca Froes Rocha, Zachary T Berndsen, David Baker, Neil P King, Rogier W Sanders, John P Moore, Shane Crotty, Max Crispin, David C Montefiori, Dennis R Burton, William R Schief, Guido Silvestri, Andrew B Ward

Journal: Nat Commun

PubMed ID: 34376662

Doi: 10.1038/s41467-021-25087-4

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Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycans

Authors: Léa Chuzel, Samantha L Fossa, Madison L Boisvert, Samanta Cajic, René Hennig, Mehul B Ganatra, Udo Reichl, Erdmann Rapp, Christopher H Taron

Journal: Microb Cell Fact

PubMed ID: 34419057

Doi: 10.1186/s12934-021-01652-w

Products & Services: Codon Optimization

Functional Insights into Silymarin as an Antiviral Agent against Enterovirus A71 (EV-A71)

Authors: Salima Lalani, Malihe Masomian, Chit Laa Poh

Journal: Int J Mol Sci

PubMed ID: 34445463

Doi: 10.3390/ijms22168757

Products & Services: Plasmid DNA Preparation

Author Correction: Identification, characterization and control of a sequence variant in monoclonal antibody drug product: a case study

Authors: Anushikha Thakur, Rekha Nagpal, Avik Kumar Ghosh, Deepak Gadamshetty, Sirisha Nagapattinam, Malini Subbarao, Shreshtha Rakshit, Sneha Padiyar, Suma Sreenivas, Nagaraja Govindappa, Harish V Pai, Ramakrishnan Melarkode Subbaraman

Journal: Sci Rep

PubMed ID: 34462514

Doi: 10.1038/s41598-021-96916-1

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N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization

Authors: Michael J Currie, Lavanyaa Manjunath, Christopher R Horne, Phillip M Rendle, Ramaswamy Subramanian, Rosmarie Friemann, Antony J Fairbanks, Andrew C Muscroft-Taylor, Rachel A North, Renwick C J Dobson

Journal: J Biol Chem

PubMed ID: 34437902

Doi: 10.1016/j.jbc.2021.101113

Products & Services: Plasmid DNA Preparation

Influence of Fc modifications and IgG subclass on biodistribution of humanized antibodies targeting L1CAM

Authors: Sai Kiran Sharma, Maya Suzuki, Hong Xu, Joshua A Korsen, Zachary Samuels, Hongfen Guo, Brandon Nemieboka, Alessandra Piersigilli, Kimberly J Edwards, Nai-Kong Cheung, Jason S Lewis

Journal: J Nucl Med

PubMed ID: 34353869

Doi: 10.2967/jnumed.121.262383

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Cas9-derived peptides presented by MHC Class II that elicit proliferation of CD4 T-cells

Authors: Vijaya L Simhadri, Louis Hopkins, Joseph R McGill, Brian R Duke, Swati Mukherjee, Kate Zhang, Zuben E Sauna

Journal: Nat Commun

PubMed ID: 34429421

Doi: 10.1038/s41467-021-25414-9

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Evaluation of two Plasmodium vivax sexual stage antigens as transmission-blocking vaccine candidates

Authors: Yongzhe Zhang, Fei Liu, Yan Zhao, Fan Yang, Jie Bai, Xitong Jia, Wanlapa Roobsoong, Jetsumon Sattabongkot, Liwang Cui, Yaming Cao, Enjie Luo, Meilian Wang

Journal: Parasit Vectors

PubMed ID: 34399829

Doi: 10.1186/s13071-021-04909-w

Products & Services: Codon Optimization

Butyryl/Caproyl-CoA:Acetate CoA-transferase: cloning, expression and characterization of the key enzyme involved in medium-chain fatty acid biosynthesis

Authors: Qingzhuoma Yang, Shengtao Guo, Qi Lu, Yong Tao, Decong Zheng, Qinmao Zhou, Jun Liu

Journal: Biosci Rep

PubMed ID: 34338280

Doi: 10.1042/BSR20211135

Products & Services: Protein and Antibody Isolation