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TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity

Authors: Sarah C Atkinson, Steven M Heaton, Michelle D Audsley, Oded Kleifeld, Natalie A Borg

Journal: Int J Mol Sci

PubMed ID: 34445801

Doi: 10.3390/ijms22169094

Products & Services: Bacterial Expression

Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex

Authors: Weifeng Liu, Zachary Maben, Carole Wang, Kevin C Lindquist, Manqing Li, Vinayak Rayannavar, Ilsel Lopez Armenta, Andrew Nager, Edward Pascua, Pawel K Dominik, David Oyen, Hui Wang, Rachel Carson Roach, Corey M Allan, Lidia Mosyak, Javier Chaparro-Riggers

Journal: J Biol Chem

PubMed ID: 34419446

Doi: 10.1016/j.jbc.2021.101102

Products & Services: Polyclonal Antibody Services

Haploinsufficiency of SF3B2 causes craniofacial microsomia

Authors: Andrew T Timberlake, Casey Griffin, Carrie L Heike, Anne V Hing, Michael L Cunningham, David Chitayat, Mark R Davis, Soghra J Doust, Amelia F Drake, Milagros M Duenas-Roque, Jack Goldblatt, Jonas A Gustafson, Paula Hurtado-Villa, Alexis Johns, Natalya Karp, Nigel G Laing, Leanne Magee, Sureni V Mullegama, Harry Pachajoa, Gloria L Porras-Hurtado, Rhonda E Schnur, Jennie Slee, Steven L Singer, David A Staffenberg, Andrew E Timms, Cheryl A Wise, Ignacio Zarante, Jean-Pierre Saint-Jeannet, Daniela V Luquetti

Journal: Nat Commun

PubMed ID: 34344887

Doi: 10.1038/s41467-021-24852-9

Products & Services: Mammalian Expression

An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates

Authors: Nerea Zabaleta, Wenlong Dai, Urja Bhatt, Cécile Hérate, Pauline Maisonnasse, Jessica A Chichester, Julio Sanmiguel, Reynette Estelien, Kristofer T Michalson, Cheikh Diop, Dawid Maciorowski, Nathalie Dereuddre-Bosquet, Mariangela Cavarelli, Anne-Sophie Gallouët, Thibaut Naninck, Nidhal Kahlaoui, Julien Lemaitre, Wenbin Qi, Elissa Hudspeth, Allison Cucalon, Cecilia D Dyer, M Betina Pampena, James J Knox, Regina C LaRocque, Richelle C Charles, Dan Li, Maya Kim, Abigail Sheridan, Nadia Storm, Rebecca I Johnson, Jared Feldman, Blake M Hauser, Vanessa Contreras, Romain Marlin, Raphaël Ho Tsong Fang, Catherine Chapon, Sylvie van der Werf, Eric Zinn, Aisling Ryan, Dione T Kobayashi, Ruchi Chauhan, Marion McGlynn, Edward T Ryan, Aaron G Schmidt, Brian Price, Anna Honko, Anthony Griffiths, Sam Yaghmour, Robert Hodge, Michael R Betts, Mason W Freeman, James M Wilson, Roger Le Grand, Luk H Vandenberghe

Journal: Cell Host Microbe

PubMed ID: 34428428

Doi: 10.1016/j.chom.2021.08.002

Products & Services: Monoclonal Antibody Services

Failure of Diphtheria Toxin Model to Induce Parkinson-Like Behavior in Mice

Authors: Lucie Valek, Irmgard Tegeder

Journal: Int J Mol Sci

PubMed ID: 34502404

Doi: 10.3390/ijms22179496

Products & Services: Endotoxin Detection & Removal System

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue

Authors: Juan Luis Pacheco-Garcia, Ernesto Anoz-Carbonell, Pavla Vankova, Adithi Kannan, Rogelio Palomino-Morales, Noel Mesa-Torres, Eduardo Salido, Petr Man, Milagros Medina, Athi N Naganathan, Angel L Pey

Journal: Redox Biol

PubMed ID: 34537677

Doi: 10.1016/j.redox.2021.102112

Products & Services: Mutagenesis Services

Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M vaccination

Authors: Matthew J Gorman, Nita Patel, Mimi Guebre-Xabier, Alex L Zhu, Caroline Atyeo, Krista M Pullen, Carolin Loos, Yenny Goez-Gazi, Ricardo Carrion, Jing-Hui Tian, Dansu Yuan, Kathryn A Bowman, Bin Zhou, Sonia Maciejewski, Marisa E McGrath, James Logue, Matthew B Frieman, David Montefiori, Colin Mann, Sharon Schendel, Fatima Amanat, Florian Krammer, Erica Ollmann Saphire, Douglas A Lauffenburger, Ann M Greene, Alyse D Portnoff, Michael J Massare, Larry Ellingsworth, Gregory Glenn, Gale Smith, Galit Alter

Journal: Cell Rep Med

PubMed ID: 34485950

Doi: 10.1016/j.xcrm.2021.100405

Products & Services: Insect Expression

Third dose of the BNT162b2 vaccine in heart transplant recipients: Immunogenicity and clinical experience

Authors: Yael Peled, Eilon Ram, Jacob Lavee, Amit Segev, Shlomi Matezki, Anat Wieder-Finesod, Rebecca Halperin, Michal Mandelboim, Victoria Indenbaum, Itzchak Levy, Leonid Sternik, Ehud Raanani, Arnon Afek, Yitshak Kreiss, Yaniv Lustig, Galia Rahav

Journal: J Heart Lung Transplant

PubMed ID: 34565682

Doi: 10.1016/j.healun.2021.08.010

Products & Services: Serology SARS-Cov-2 detection kits

Nature and Dimensions of Systemic Hyperinflammation and its Attenuation by Convalescent Plasma in Severe COVID-19

Authors: Purbita Bandopadhyay, Ranit D'Rozario, Abhishake Lahiri, Jafar Sarif, Yogiraj Ray, Shekhar Ranjan Paul, Rammohan Roy, Rajshekhar Maiti, Kausik Chaudhuri, Saugata Bagchi, Ayan Maiti, Mohammed Masoom Perwez, Biswanath Sharma Sarkar, Devlina Roy, Rahul Chakraborty, Janani Srinivasa Vasudevan, Sachin Sharma, Durba Biswas, Chikam Maiti, Bibhuti Saha, Prasun Bhattacharya, Rajesh Pandey, Shilpak Chatterjee, Sandip Paul, Dipyaman Ganguly

Journal: J Infect Dis

PubMed ID: 34398242

Doi: 10.1093/infdis/jiab010

Products & Services: Recombinant Antibody Expression

Simultaneous evaluation of antibodies that inhibit SARS-CoV-2 variants via multiplex assay

Authors: Ester Lopez, Ebene R Haycroft, Amy Adair, Francesca L Mordant, Matthew T O'Neill, Phillip Pymm, Samuel J Redmond, Wen Shi Lee, Nicholas A Gherardin, Adam K Wheatley, Jennifer A Juno, Kevin J Selva, Samantha K Davis, Samantha L Grimley, Leigh Harty, Damian Fj Purcell, Kanta Subbarao, Dale I Godfrey, Stephen J Kent, Wai-Hong Tham, Amy W Chung

Journal: JCI Insight

PubMed ID: 34251356

Doi: 10.1172/jci.insight.150012

Products & Services: Recombinant Antibody Expression