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Structures of complete HIV-1 TAR RNA portray a dynamic platform poised for protein binding and structural remodeling

Authors: Charles Bou-Nader, Katie A Link, Krishna C Suddala, Jay R Knutson, Jinwei Zhang

Journal: Nature Communications

PubMed ID: 40050622

Doi: 10.1038/s41467-025-57519-w

Products & Services: Peptide Synthesis

Blockade of ZMIZ1-GATA4 Axis Regulation Restores Youthfulness to Aged Cartilage

Authors: Jiho Nam, Hyunmin Woo, Jihye Yang, Seok Jung Kim, Kwang Pyo Lee, Ji Hoon Yu, Tae Joo Park, Seong-Il Eyun, Siyoung Yang

Journal: Advanced Science

PubMed ID: 40040621

Doi: 10.1002/advs.202404311

Products & Services: Chemicals

Structural dynamics of DNA unwinding by a replicative helicase

Authors: Taha Shahid, Ammar U Danazumi, Muhammad Tehseen, Lubna Alhudhali, Alice R Clark, Christos G Savva, Samir M Hamdan, Alfredo De Biasio

Journal: Nature

PubMed ID: 40108462

Doi: 10.1038/s41586-025-08766-w

Products & Services: Custom Vector Construction

Plant essential oil targets TRPV3 for skin renewal and structural mechanism of action

Authors: Yang Li, Xuteng Lu, Xufeng Cheng, Keyu Xia, Junyan Hu, Peiyu Wang, Peiyuan Pang, Bomin Gao, Demeng Sun, Zhuzhen Zhang, Dongdong Li, Zengqin Deng, Changlin Tian, Chang Xie, Jing Yao

Journal: Nature Communications

PubMed ID: 40108208

Doi: 10.1038/s41467-025-58033-9

Products & Services: Protein and Antibody Isolation

Structural basis of gap-filling DNA synthesis in the nucleosome by DNA Polymerase β

Authors: Tyler M Weaver, Benjamin J Ryan, Spencer H Thompson, Adil S Hussen, Jonah J Spencer, Zhen Xu, Nicholas J Schnicker, Bret D Freudenthal

Journal: Nature Communications

PubMed ID: 40097433

Doi: 10.1038/s41467-025-57915-2

Products & Services: Codon Optimization

Structural recognition and stabilization of tyrosine hydroxylase by the J-domain protein DNAJC12

Authors: Mary Dayne S Tai, Lissette Ochoa, Marte I Flydal, Lorea Velasco-Carneros, Jimena Muntaner, César Santiago, Gloria Gamiz-Arco, Fernando Moro, Kunwar Jung-Kc, David Gil-Cantero, Miguel Marcilla, Juha P Kallio, Arturo Muga, José María Valpuesta, Jorge Cuéllar, Aurora Martinez

Journal: Nature Communications

PubMed ID: 40113792

Doi: 10.1038/s41467-025-57733-6

Mimicry of molecular glues using dual covalent chimeras

Authors: Eden Kapcan, Karolina Krygier, Maya da Luz, Nickolas J Serniuck, Ali Zhang, Jonathan Bramson, Anthony F Rullo

Journal: Nature Communications

PubMed ID: 40128528

Doi: 10.1038/s41467-025-58083-z

Products & Services: Antibody Services

Conformational reorganization and phase separation drive hyper-editing of ADR-2-ADBP-1 complex

Authors: Jianqiang Mu, Cang Wu, Kaiming Xu, Xingang Liu, Yajuan Fu, Zhen Zhang, Jingwei Yu, Chenyang Xue, Zi Wang, Xinmeng Chen, Yanhong Chen, Guangshuo Ou, Zhongmin Liu

Journal: Nucleic Acids Res

PubMed ID: 40037706

Doi: 10.1093/nar/gkaf148

Resilient Membranized Coacervates Formed through Spontaneous Wrapping of Heat-Destabilized Lipid Bilayers around Coacervate Droplets

Authors: Sadaf Javed, Evan Spruijt

Journal: Advanced Science

PubMed ID: 40116289

Doi: 10.1002/advs.202412312

Bacterial Hachiman complex executes DNA cleavage for antiphage defense

Authors: Yongqing Cui, Zhikang Dai, Yufei Ouyang, Chunyang Fu, Yanjing Wang, Xueting Chen, Kaiyue Yang, Shuyue Zheng, Wenwen Wang, Pan Tao, Zeyuan Guan, Tingting Zou

Journal: Nature Communications

PubMed ID: 40097437

Doi: 10.1038/s41467-025-57851-1