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Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy

Authors: Sheng-Li Ming , Shuang Zhang , Qi Wang , Lei Zeng , Lu-Yu Zhou , Meng-Di Wang , Ying-Xian Ma , Li-Qiang Han , Kai Zhong , He-Shui Zhu , Yi-Lin Bai , Guo-Yu Yang , Jiang Wang , Bei-Bei Chu

Journal: Autophagy

PubMed ID: 34822318

Doi: 10.1080/15548627.2021.2002101

Products & Services: Catalog Antibodies

Cyclic peptides with a distinct arginine-fork motif recognize the HIV trans-activation response RNA in vitro and in cells

Authors: Sai Shashank Chavali, Sachitanand M Mali, Rachel Bonn, Abhijith Saseendran Anitha, Ryan P Bennett, Harold C Smith, Rudi Fasan, Joseph E Wedekind

Journal: J Biol Chem.

PubMed ID: 34767799

Doi: 10.1016/j.jbc.2021.101390

Products & Services: Peptide Synthesis

Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants

Authors: Matthew McCallum, Alexandra C Walls, Kaitlin R Sprouse, John E Bowen, Laura E Rosen, Ha V Dang, Anna De Marco, Nicholas Franko, Sasha W Tilles, Jennifer Logue, Marcos C Miranda, Margaret Ahlrichs, Lauren Carter, Gyorgy Snell, Matteo Samuele Pizzuto, Helen Y Chu, Wesley C Van Voorhis, Davide Corti, David Veesler

Journal: Science

PubMed ID: 34751595

Doi: 10.1126/science.abl8506

Products & Services: Serology SARS-Cov-2 detection kits

Immune Responses to a Single Dose of the AZD1222/Covishield Vaccine at 16 Weeks in Individuals in Sri Lanka

Authors: Chandima Jeewandara, Dinuka Guruge, Pradeep Darshana Pushpakumara, Achala Kamaladasa, Inoka Sepali Aberathna, Shyrar Tanussiya Ramu, Banuri Gunasekera, Ayesha Wijesinghe, Osanda Dissanayake, Heshan Kuruppu, Thushali Ranasinghe, Deshni Jayathilaka, Shashika Dayarathna, Dinithi Ekanayake, Jeewantha Jayamali, Nayanathara Gamalath, Anushika Mudunkotiwa, Gayasha Somathilake, Madhushika Dissanayake, Michael Harvie, Thashmi Nimasha, Deshan Madusanka, Tibutius Jayadas, Ruwan Wijayamuni, Lisa Schimanski, Pramila Rijal, Tiong K Tan, Alain Townsend, Graham S Ogg, Gathsaurie Neelika Malavige

Journal: J Immunol

PubMed ID: 34750205

Doi: 10.4049/jimmunol.2100762

Products & Services: Recombinant Antibody Expression

α-Klotho released from HK-2 cells inhibits osteogenic differentiation of renal interstitial fibroblasts by inactivating the Wnt-β-catenin pathway

Authors: Zewu Zhu, Shuhao Ruan, Yingcheng Jiang, Fang Huang, Weiping Xia, Jinbo Chen, Yu Cui, Cheng He, Feng Zeng, Yang Li, Zhiyong Chen, Hequn Chen

Journal: Cell Mol Life Sci

PubMed ID: 34724098

Doi: 10.1007/s00018-021-03972-x

Products & Services: Protein and Antibody Isolation

Hydrolytically Stable Maleimide-End-Functionalized Polymers for Site-Specific Protein Conjugation

Authors: Thaiesha A Wright, Monica Sharfin Rahman, Camaryn Bennett, Madolynn R Johnson, Henry Fischesser, Natasha Ram, Amoni Tyler, Richard C Page, Dominik Konkolewicz

Journal: Bioconjug Chem

PubMed ID: 34730954

Doi: 10.1021/acs.bioconjchem.1c00487

Products & Services: Plasmid DNA Preparation

LDH nanoparticle adjuvant subunit vaccine induces an effective immune response for porcine epidemic diarrhea virus

Authors: Danyi Shi, Baochao Fan, Bing Sun, Jinzhu Zhou, Yongxiang Zhao, Rongli Guo, Zengjun Ma, Tao Song, Huiying Fan, Jizong Li, Li Li, Bin Li

Journal: Virology

PubMed ID: 34739917

Doi: 10.1016/j.virol.2021.10.010

Products & Services: Plasmid DNA Preparation

Polyactin A and CpG enhance inactivated Pseudomonas plecoglossicida vaccine potency in large yellow croaker (Larimichthys crocea)

Authors: Wenwen Wang, Wei Wang, Wenjun Xu, Qin Liu, Yuanxing Zhang, Xiaohong Liu

Journal: Fish Shellfish Immunol

PubMed ID: 34780977

Doi: 10.1016/j.fsi.2021.11.008

Products & Services: Plasmid DNA Preparation

STING inhibition accelerates the bone healing process while enhancing type H vessel formation

Authors: Xiaojun Chen, Wenxin He, Mengzhe Sun, Yingjie Yan, Yichuan Pang, Gang Chai

Journal: FASEB J

PubMed ID: 34694030

Doi: 10.1096/fj.202100069RR

Products & Services: Nucleic Acid Purification

Structural basis and mechanism of activation of two different families of G proteins by the same GPCR

Authors: Kamela O Alegre, Navid Paknejad, Minfei Su, Jian-Shu Lou, Jianyun Huang, Kelsey D Jordan, Edward T Eng, Joel R Meyerson, Richard K Hite, Xin-Yun Huang

Journal: Nat Struct Mol Biol

PubMed ID: 34759376

Doi: 10.1038/s41594-021-00679-2

Products & Services: Mutant Libraries