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Beyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis

Authors: Marketa Koberska, Ludmila Vesela, Vladimir Vimberg, Jakub Lenart, Jana Vesela, Zdenek Kamenik, Jiri Janata, Gabriela Balikova Novotna

Journal: MBio

PubMed ID: 34488446

Doi: 10.1128/mBio.01731-21

Products & Services: Catalog Antibodies

Control of Gene Expression With Quercetin-Responsive Modular Circuits

Authors: Fernanda Miyuki Kashiwagi, Brenno Wendler Miranda, Fabio de Oliveira Pedrosa, Emanuel Maltempi de Souza, Marcelo Müller-Santos

Journal: Front Bioeng Biotechnol

PubMed ID: 34604189

Doi: 10.3389/fbioe.2021.730967

Products & Services: Bacterial Expression

A Neuroprotective Bovine Colostrum Attenuates Apoptosis in Dexamethasone-Treated MC3T3-E1 Osteoblastic Cells

Authors: Sagrario Martin-Aragon, Paloma Bermejo-Bescós, Juana Benedí, Carlos Raposo, Franklim Marques, Eirini K Kydonaki, Paraskevi Gkiata, Yiannis Koutedakis, Georgia Ntina, Andres E Carrillo, Tânia Amorim

Journal: Int J Mol Sci

PubMed ID: 34638536

Doi: 10.3390/ijms221910195

Products & Services: Polyclonal Antibody Services

Novel virus-like nanoparticle vaccine effectively protects animal model from SARS-CoV-2 infection

Authors: Qibin Geng, Wanbo Tai, Victoria K Baxter, Juan Shi, Yushun Wan, Xiujuan Zhang, Stephanie A Montgomery, Sharon A Taft-Benz, Elizabeth J Anderson, Audrey C Knight, Kenneth H Dinnon, Sarah R Leist, Ralph S Baric, Jian Shang, Sung-Wook Hong, Aleksandra Drelich, Chien-Te K Tseng, Marc Jenkins, Mark Heise, Lanying Du, Fang Li

Journal: PLoS Pathog

PubMed ID: 34492082

Doi: 10.1371/journal.ppat.1009897

Products & Services: Protein and Antibody Isolation

Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease

Authors: Shanshan Li, Kan-Yen Hsieh, Shih-Chieh Su, Grigore D Pintilie, Kaiming Zhang, Chung-I Chang

Journal: J Biol Chem

PubMed ID: 34563541

Doi: 10.1016/j.jbc.2021.101239

Products & Services: Protein Electrophoresis and Western

Structural insights into the activation of human calcium-sensing receptor

Authors: Xiaochen Chen, Lu Wang, Qianqian Cui, Zhanyu Ding, Li Han, Yongjun Kou, Wenqing Zhang, Haonan Wang, Xiaomin Jia, Mei Dai, Zhenzhong Shi, Yuying Li, Xiyang Li, Yong Geng

Journal: Elife

PubMed ID: 34467854

Doi: 10.7554/eLife.68578

Products & Services: Catalog Peptides

Neuromedin B receptor stimulation of Cav32 T-type Ca channels in primary sensory neurons mediates peripheral pain hypersensitivity

Authors: Yuan Zhang, Zhiyuan Qian, Dongsheng Jiang, Yufang Sun, Shangshang Gao, Xinghong Jiang, Hua Wang, Jin Tao

Journal: Theranostics

PubMed ID: 34646374

Doi: 10.7150/thno.62255

Products & Services: Peptide Synthesis

Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis

Authors: Fredarla S Miller, Kathryn K Crone, Matthew R Jensen, Sudipta Shaw, William R Harcombe, Mikael H Elias, Michael F Freeman

Journal: Nat Commun

PubMed ID: 34504067

Doi: 10.1038/s41467-021-25575-7

Products & Services: Bacterial Expression

Cellular retinoid-binding proteins transfer retinoids to human cytochrome P450 27C1 for desaturation

Authors: Sarah M Glass, F Peter Guengerich

Journal: J Biol Chem

PubMed ID: 34480899

Doi: 10.1016/j.jbc.2021.101142

Products & Services: Mutagenesis Services

Preclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel disease

Authors: Kevin J Roberts, Marion F Cubitt, Timothy M Carlton, Lurdes Rodrigues-Duarte, Luana Maggiore, Ray Chai, Simon Clare, Katherine Harcourt, Thomas T MacDonald, Keith P Ray, Anna Vossenkämper, Michael R West, J Scott Crowe

Journal: Sci Rep

PubMed ID: 34593832

Doi: 10.1038/s41598-021-97236-0

Products & Services: Monoclonal Antibody Services