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Cellular retinoid-binding proteins transfer retinoids to human cytochrome P450 27C1 for desaturation

Authors: Sarah M Glass, F Peter Guengerich

Journal: J Biol Chem

PubMed ID: 34480899

Doi: 10.1016/j.jbc.2021.101142

Products & Services: Mutagenesis Services

Preclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel disease

Authors: Kevin J Roberts, Marion F Cubitt, Timothy M Carlton, Lurdes Rodrigues-Duarte, Luana Maggiore, Ray Chai, Simon Clare, Katherine Harcourt, Thomas T MacDonald, Keith P Ray, Anna Vossenkämper, Michael R West, J Scott Crowe

Journal: Sci Rep

PubMed ID: 34593832

Doi: 10.1038/s41598-021-97236-0

Products & Services: Monoclonal Antibody Services

Newt regeneration genes regulate Wingless signaling to restore patterning in eye

Authors: Abijeet Singh Mehta, Prajakta Deshpande, Anuradha Venkatakrishnan Chimata, Panagiotis A Tsonis, Amit Singh

Journal: iScience

PubMed ID: 34746690

Doi: 10.1016/j.isci.2021.103166

Products & Services: ORF cDNA Clones/MolecularCloud

Nasal Immunization With Small Molecule Mast Cell Activators Enhance Immunity to Co-Administered Subunit Immunogens

Authors: Brandi T Johnson-Weaver, Hae Woong Choi, Hang Yang, Josh A Granek, Cliburn Chan, Soman N Abraham, Herman F Staats

Journal: Front Immunol

PubMed ID: 34566991

Doi: 10.3389/fimmu.2021.730346

Products & Services: Catalog Antibodies

Determination of Chinese hamster ovary (CHO) cell densities and antibody titers from small volumes of cell culture supernatants using multivariate analysis and partial least squares regression of UV-Vis spectra

Authors: Salinthip Jarusintanakorn, Chutima Phechkrajang, Putthiporn Khongkaew, Enrico Mastrobattista, Montarop Yamabhai

Journal: Anal Bioanal Chem

PubMed ID: 34476523

Doi: 10.1007/s00216-021-03549-4

Products & Services: Protein and Antibody Isolation

Ferulic Acid Metabolites Attenuate LPS-Induced Inflammatory Response in Enterocyte-like Cells

Authors: Gabriele Serreli, Micaela Rita Naitza, Sonia Zodio, Vera Piera Leoni, Martina Spada, Maria Paola Melis, Anna Boronat, Monica Deiana

Journal: Nutrients

PubMed ID: 34579029

Doi: 10.3390/nu13093152

Products & Services: Protein and Antibody Isolation

Manipulating turn residues on de novo designed β-hairpin peptides for selectivity against drug-resistant bacteria

Authors: Nhan D T Tram, Vanitha Selvarajan, Alister Boags, Devika Mukherjee, Jan K Marzinek, Bernadette Cheng, Zi-Chen Jiang, Pascal Goh, Jun-Jie Koh, Jeanette W P Teo, Peter J Bond, Pui Lai Rachel Ee

Journal: Acta Biomater

PubMed ID: 34506975

Doi: 10.1016/j.actbio.2021.09.004

Products & Services: Molecular Biology Tools

A novel intronic circular RNA, circGNG7, inhibits head and neck squamous cell carcinoma progression by blocking the phosphorylation of heat shock protein 27 at Ser78 and Ser82

Authors: Houyu Ju, Zhenrong Hu, Dongliang Wei, Jinyun Huang, Xinyi Zhang, Mengyu Rui, Zhi Li, Xiaomeng Zhang, Jingzhou Hu, Wei Guo, Guoxin Ren

Journal: Cancer Commun (Lond)

PubMed ID: 34498800

Doi: 10.1002/cac2.12213

Products & Services: Plasmid DNA Preparation

Development and characterization of a unique anti-IgE mouse monoclonal antibody cross-reactive between human and canine IgE

Authors: Akiko Kumagai, Takuya Nara, Mizuho Uematsu, Yoko Kakinuma, Takashi Saito, Kenichi Masuda

Journal: Immun Inflamm Dis

PubMed ID: 34533288

Doi: 10.1002/iid3.531

Products & Services: Gene Synthesis

Targeting the VCP-binding motif of ataxin-3 improves phenotypes in Drosophila models of Spinocerebellar Ataxia Type 3

Authors: Sean L Johnson, Kozeta Libohova, Jessica R Blount, Alyson L Sujkowski, Matthew V Prifti, Wei-Ling Tsou, Sokol V Todi

Journal: Neurobiol Dis

PubMed ID: 34563642

Doi: 10.1016/j.nbd.2021.105516

Products & Services: Gene Synthesis