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Structure, catalysis, chitin transport, and selective inhibition of chitin synthase

Authors: Dan-Dan Chen, Zhao-Bin Wang, Le-Xuan Wang, Peng Zhao, Cai-Hong Yun, Lin Bai

Journal: Nat Commun

PubMed ID: 37553334

Doi: 10.1038/s41467-023-40479-4

Products & Services: Custom DNA/RNA Oligos

A new compact adenine base editor generated through deletion of HNH and REC2 domain of SpCas9

Authors: Yuqiang Qian , Di Wang , Wenchao Niu , Ding Zhao , Jinze Li , Zhiquan Liu , Xun Gao , Yang Han , Liangxue Lai , Zhanjun Li

Journal: BMC Biol .

PubMed ID: 37434184

Doi: 10.1186/s12915-023-01644-9

Products & Services: Synthetic sgRNA and crRNA Service

Glc7/PP1 dephosphorylates histone H3T11 to regulate autophagy and telomere silencing in response to nutrient availability

Authors: Xinyu Zhang, Qi Yu, Yinsheng Wu, Yuan Zhang, Yi He, Rongsha Wang, Xilan Yu,Shanshan Li

Journal: Cell Discovery

Doi: 10.1038/s41421-023-00551-1

Products & Services: Antibody Modification and Purification Services

Chemo-enzymatic cascades producing 2,5- furandicarboxylic acid precursors via D-gluconate “barbell oxidation” and dehydration

Authors: Jiao Chen, a,b Jiali Cai,c Feng Sha,d Wenjun Sun,a Xilei Lyu,e Yonghui Chang,f Fei Cao, Lili Zhao, Hongli Wu and Pingkai Ouyang

Journal: Green Chem.

Doi: 10.1039/d3gc01493b

Products & Services: Gene Synthesis

Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells

Authors: Praveen Kumar Jadi, Alpana Dave, Rahaf Issa, Khatija Tabbasum, Katarzyna Okurowska, Apurwa Samarth, Lucy Urwin, Luke R Green, Lynda J Partridge, Sheila MacNeil, Prashant Garg, Peter N Monk, Sanhita Roy

Journal: Ocul Surf

PubMed ID: 37406881

Doi: 10.1016/j.jtos.2023.07.001

Products & Services: Molecular Biology Reagents

A positively tuned voltage indicator for extended electrical recordings in the brain

Authors: S Wenceslao Evans, Dong-Qing Shi, Mariya Chavarha, Mark H Plitt, Jiannis Taxidis, Blake Madruga, Jiang Lan Fan, Fuu-Jiun Hwang, Siri C van Keulen, Carl-Mikael Suomivuori, Michelle M Pang, Sharon Su, Sungmoo Lee, Yukun A Hao, Guofeng Zhang, Dongyun Jiang, Lagnajeet Pradhan, Richard H Roth, Yu Liu, Conor C Dorian, Austin L Reese, Adrian Negrean, Attila Losonczy, Christopher D Makinson, Sui Wang, Thomas R Clandinin, Ron O Dror, Jun B Ding, Na Ji, Peyman Golshani, Lisa M Giocomo, Guo-Qiang Bi, Michael Z Lin

Journal: Nat Methods

PubMed ID: 37429962

Doi: 10.1038/s41592-023-01913-z

Products & Services: Molecular Biology Reagents

Process Robustness in Lipid Nanoparticle Production: A Comparison of Microfluidic and Turbulent Jet Mixing

Authors: Matthew N O'Brien Laramy, Antonio P Costa, Yareli Maciel Cebrero, Johnson Joseph, Apoorva Sarode, Nanzhi Zang, Lee Joon Kim, Kate Hofmann, Shirley Wang, Alexandre Goyon, Stefan G Koenig, Michal Hammel, Greg L Hura

Journal: Mol Pharm

PubMed ID: 37462906

Doi: 10.1021/acs.molpharmaceut.3c00390

Products & Services: Proteins, Expression, Isolation and Analysis

Decoding a cryptic mechanism of metronidazole resistance among globally disseminated fluoroquinolone-resistant Clostridioides difficile

Authors: Abiola O Olaitan, Chetna Dureja, Madison A Youngblom, Madeline A Topf, Wan-Jou Shen, Anne J Gonzales-Luna, Aditi Deshpande, Kirk E Hevener, Jane Freeman, Mark H Wilcox, Kelli L Palmer, Kevin W Garey, Caitlin S Pepperell, Julian G Hurdle

Journal: Nat Commun

PubMed ID: 37438331

Doi: 10.1038/s41467-023-39429-x

Products & Services: Molecular Biology Reagents

Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection

Authors: Gregory M Martin, Jonathan L Torres, Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Grace Gibson, Re'em Moskovitz, Nathan Beutler, Diana D Jung, Jeffrey Copps, Wen-Hsin Lee, Gonzalo Gonzalez-Paez, Daniel Emerling, Randall S MacGill, Emily Locke, C Richter King, Fidel Zavala, Ian A Wilson, Andrew B Ward

Journal: Nat Commun

PubMed ID: 37507365

Doi: 10.1038/s41467-023-40151-x

Products & Services: Molecular Biology Reagents

Tetracycline-modifying enzyme SmTetX from Stenotrophomonas maltophilia

Authors: Martin Malý, Petr Kolenko, Jan Stránský, Leona Švecová, Jarmila Dušková, Tomáš Koval', Tereza Skálová, Mária Trundová, Kristýna Adámková, Jiří Černý, Paulína Božíková, Jan Dohnálek

Journal: Acta Crystallogr F Struct Biol Commun

PubMed ID: 37405486

Doi: 10.1107/S2053230X23005381

Products & Services: Proteins, Expression, Isolation and Analysis

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