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The glycan hole area of HIV-1 envelope trimers contributes prominently to the induction of autologous neutralization

Authors: Anna Schorcht, Christopher A Cottrell, Pavel Pugach, Rajesh P Ringe, Alvin X Han, Joel D Allen, Tom L G M van den Kerkhof, Gemma E Seabright, Edith E Schermer, Thomas J Ketas, Judith A Burger, Jelle van Schooten, Celia C LaBranche, Gabriel Ozorowski, Natalia de Val, Daniel L V Bader, Hanneke Schuitemaker, Colin A Russell, David C Montefiori, Marit J van Gils, Max Crispin, P J Klasse, Andrew B Ward, John P Moore, Rogier W Sanders

Journal: J Virol

PubMed ID: 34669426

Doi: 10.1128/JVI.01552-21

Products & Services: Codon Optimization

A dedicated flavin-dependent monooxygenase catalyzes the hydroxylation of demethoxyubiquinone into ubiquinone (coenzyme Q) in Arabidopsis

Authors: Scott Latimer, Shea A Keene, Lauren R Stutts, Antoine Berger, Ann C Bernert, Eric Soubeyrand, Janet Wright, Catherine F Clarke, Anna K Block, Thomas A Colquhoun, Christian Elowsky, Alan Christensen, Mark A Wilson, Gilles J Basset

Journal: J Biol Chem

PubMed ID: 34626646

Doi: 10.1016/j.jbc.2021.101283

Products & Services: Gene Synthesis

Minimalistic mycoplasmas harbor different functional toxin-antitoxin systems

Authors: Virginia Hill, Hatice Akarsu, Rubén Sánchez Barbarroja, Valentina L Cippà, Peter Kuhnert, Martin Heller, Laurent Falquet, Manfred Heller, Michael H Stoffel, Fabien Labroussaa, Joerg Jores

Journal: PLoS Genet

PubMed ID: 34673769

Doi: 10.1371/journal.pgen.1009365

Products & Services: Catalog Antibodies

The intrinsic kinase activity of BRD4 spans its BD2-B-BID domains

Authors: Jocelyn D Weissman, Amit K Singh, Ballachanda N Devaiah, Peter Schuck, Ross C LaRue, Dinah S Singer

Journal: J Biol Chem

PubMed ID: 34688663

Doi: 10.1016/j.jbc.2021.101326

Products & Services: Protein and Antibody Isolation

Human Antibody Domains and Fragments Targeting Neutrophil Elastase as Candidate Therapeutics for Cancer and Inflammation-Related Diseases

Authors: Xiaojie Chu, Zehua Sun, Du-San Baek, Wei Li, John W Mellors, Steven D Shapiro, Dimiter S Dimitrov

Journal: Int J Mol Sci

PubMed ID: 34681796

Doi: 10.3390/ijms222011136

Products & Services: Plasmid DNA Preparation

A New Hybrid Protein Is a Novel Regulator for Experimental Colitis in Rats

Authors: Kohki Okada, Masaki Ikemoto

Journal: Inflammation

PubMed ID: 34628574

Doi: 10.1007/s10753-021-01537-5

Products & Services: Protein and Antibody Isolation

Characterization of a P-glycoprotein drug transporter from Toxocara canis with a novel pharmacological profile

Authors: Jeba R J Jesudoss Chelladurai, Douglas E Jones, Matthew T Brewer

Journal: Int J Parasitol Drugs Drug Resist

PubMed ID: 34753107

Doi: 10.1016/j.ijpddr.2021.10.002

Products & Services: Catalog Peptides

Monitoring PD-1 Phosphorylation to Evaluate PD-1 Signaling during Antitumor Immune Responses

Authors: Xia Bu, Vikram R Juneja, Carol G Reynolds, Kathleen M Mahoney, Melissa T Bu, Kathleen A McGuire, Seth Maleri, Ping Hua, Baogong Zhu, Sarah R Klein, Edward A Greenfield, Philippe Armand, Jerome Ritz, Arlene H Sharpe, Gordon J Freeman

Journal: Cancer Immunol Res

PubMed ID: 34635486

Doi: 10.1158/2326-6066.CIR-21-0493

Products & Services: Peptide Synthesis

8-Hydroxyquinoline-Amino Acid Hybrids and Their Half-Sandwich Rh and Ru Complexes: Synthesis, Anticancer Activities, Solution Chemistry and Interaction with Biomolecules

Authors: Tamás Pivarcsik, Orsolya Dömötör, János P Mészáros, Nóra V May, Gabriella Spengler, Oszkár Csuvik, István Szatmári, Éva A Enyedy

Journal: Int J Mol Sci

PubMed ID: 34681939

Doi: 10.3390/ijms222011281

Products & Services: Gene Synthesis

Rapid development of analytical methods for evaluating pandemic vaccines: a COVID-19 perspective

Authors: Jeremy Baldwin, Sakshi Piplani, Isaac G Sakala, Yoshikazu Honda-Okubo, Lei Li, Nikolai Petrovsky

Journal: Bioanalysis

PubMed ID: 34645288

Doi: 10.4155/bio-2021-0096

Products & Services: Recombinant Proteins